Rinck P A, Myhr G, Smevik O, Børseth A
Universität Trondheim, Medizinische Fakultät, MR-Zentrum Trondheim, Norwegen.
Rofo. 1992 Dec;157(6):533-8. doi: 10.1055/s-2008-1033058.
The authors summarise their experience of four clinical studies with a negative oral contrast agent for magnetic resonance imaging of the abdomen and pelvis. 140 patients were enrolled in the studies. These were partly comparative studies pre- and post-contrast, partly at 0.5 and 1.5 T, partly pre-injection and post-injection of glucagon. All patients received 800 ml of a suspension of oral magnetic particles "OMP". The distribution of this contrast agent was homogeneous throughout the entire GI tract. A complete or partial signal void was observed in all patients in T1, T2-, and intermediately weighted images. Generally, diagnostic information was higher after contrast. Artifacts caused by peristalsis and movement of the diaphragm were fewer after contrast. After contrast metallic artifacts were observed in a minority of patients. Adverse events after contrast were minimal; they included nausea and vomiting.
作者总结了四项使用阴性口服造影剂进行腹部和盆腔磁共振成像的临床研究经验。140名患者参与了这些研究。这些研究部分为造影剂前后的对比研究，部分在0.5T和1.5T场强下进行，部分在注射胰高血糖素前后进行。所有患者均接受了800毫升口服磁性颗粒“OMP”混悬液。这种造影剂在整个胃肠道的分布是均匀的。在T1、T2加权和中等加权图像中，所有患者均观察到完全或部分信号缺失。一般来说，造影后诊断信息更多。造影后由蠕动和膈肌运动引起的伪影较少。造影后少数患者出现金属伪影。造影后的不良事件极少；包括恶心和呕吐。
