Wu Zhanxiong, Zhu Shanan, Bin He
College of Electrical Engineering, Zhejiang University, Hangzhou 310027, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2010 Jun;27(3):481-4.
The study of water molecule self-diffusion process is of importance not only for getting anatomical information of brain inner tissue, but also for shedding light on the diffusion process of some medicine in brain tissue. In this paper, we summarized the self-diffusion model of water molecule in brain inner tissue, and calculated the self-diffusion coefficient based on Monte Carlo simulation under different conditions. The comparison between this result and that of Latour model showed that the two self-diffusion coefficients were getting closer when the diffusion time became longer, and that the Latour model was a long time-depended self-diffusion model.
对水分子自扩散过程的研究不仅对于获取脑内组织的解剖学信息具有重要意义，而且对于阐明某些药物在脑组织中的扩散过程也很重要。在本文中，我们总结了脑内组织中水分子的自扩散模型，并基于蒙特卡罗模拟计算了不同条件下的自扩散系数。该结果与拉图尔模型结果的比较表明，随着扩散时间变长，两个自扩散系数越来越接近，并且拉图尔模型是一个长时间依赖的自扩散模型。
