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神经眼科门诊鞍上肿瘤的三年经验

Three years experience of suprasellar tumors in neuro-ophthalmology clinic.

作者信息

Aui-aree Nipat, Phruanchroen Chatmongkol, Oearsakul Thakul, Hirunpat Siriporn, Sangthong Rassamee

机构信息

Department of Ophthalmology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.

出版信息

J Med Assoc Thai. 2010 Jul;93(7):818-23.

Abstract

OBJECTIVE

To examine pre-treatment ophthalmic presentations and treatment results and to identify factors that may influence improved visual outcomes in patients with suprasellar tumor

MATERIAL AND METHOD

The medical records of patients with suprasellar tumors who were diagnosed between July 2005 and June 2008 in the neuro-ophthalmology clinic of Songklanagarind Hospital were retrospectively reviewed by two ophthalmologists. Pre-treatment ophthalmic presentations and treatment results were analyzed. Determinants of improved visual outcomes were identified by using univariate and multivariate regression analysis.

RESULTS

Of 40 patients, 55% were male and 45% were female, with a median age of 38 years. The most common pre-treatment ophthalmic presentations were blurred vision (92.5%), headache (10%) and eye pain (5%). The most common tumor was pituitary adenoma (macroadenoma and prolactinoma). Visual improvement was achieved in pituitary adenoma in 20 of 25 eyes (80%), meningioma in 8 of 12 eyes (67%) and other tumors in 2 of 5 eyes (40%). No determinants related to better visual outcomes were found.

CONCLUSION

The most common presentation of suprasellar tumor was blurred vision. There were no pre-treatment factors that related to visual outcomes in the present study.

摘要

目的

研究鞍上肿瘤患者的治疗前眼部表现及治疗结果,并确定可能影响视力改善的因素。

材料与方法

两位眼科医生对2005年7月至2008年6月期间在宋卡那加拉医院神经眼科门诊诊断为鞍上肿瘤的患者病历进行回顾性研究。分析治疗前眼部表现及治疗结果。通过单因素和多因素回归分析确定视力改善的决定因素。

结果

40例患者中,男性占55%,女性占45%,中位年龄为38岁。治疗前最常见的眼部表现为视力模糊(92.5%)、头痛(10%)和眼痛(5%)。最常见的肿瘤是垂体腺瘤(大腺瘤和催乳素瘤)。25只眼中有20只(80%)垂体腺瘤患者视力改善,12只眼中有8只(67%)脑膜瘤患者视力改善,5只眼中有2只(40%)其他肿瘤患者视力改善。未发现与更好视力结果相关的决定因素。

结论

鞍上肿瘤最常见的表现是视力模糊。本研究中未发现与视力结果相关的治疗前因素。

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