Wegener S T
University of Virginia Health Sciences Center, Charlottesville.
Curr Opin Rheumatol. 1991 Apr;3(2):300-4. doi: 10.1097/00002281-199104000-00015.
Recent findings suggest that biologic, psychologic, and social variables interact to determine an individual's response to rheumatic disease. Data indicate that specific coping responses and quality of social support modulate the psychosocial impact of the disease. Additional current developments are 1) an increased emphasis on patients' input regarding health care delivery; 2) the development of alternative methods of information dissemination; 3) identification of nonadherence to treatment regimens as an obstacle to clinical trials and to improving outcome; and 4) a trend toward the use of psychosocial assessment tools with established psychometric properties for rheumatic disease populations. A major challenge is the identification of mechanisms by which psychosocial variables interact with biologic processes.
近期研究结果表明，生物学、心理学和社会变量相互作用，共同决定个体对风湿性疾病的反应。数据显示，特定的应对反应和社会支持质量会调节该疾病的心理社会影响。当前的其他进展包括：1）更加重视患者对医疗服务提供的意见；2）开发替代的信息传播方法；3）将不遵守治疗方案认定为临床试验和改善治疗结果的障碍；4）有使用针对风湿性疾病人群、具有既定心理测量特性的心理社会评估工具的趋势。一个主要挑战是确定心理社会变量与生物学过程相互作用的机制。
