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感染与哮喘:旧观念的新认识。

Infections and asthma: new insights into old ideas.

机构信息

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2650, USA.

出版信息

Clin Exp Allergy. 2010 Aug;40(8):1142-54. doi: 10.1111/j.1365-2222.2010.03563.x.

DOI:10.1111/j.1365-2222.2010.03563.x
PMID:20649609
Abstract

A relationship between infections and allergic airway disease has long been recognized, and many reviews have been written on this topic. However, both clinical and basic science studies published in the last 3 years provide new insights into the relationship between infection and allergic conditions. In this review, we focus on these very recent studies, which address the role of infection in the development, maintenance, and exacerbation of asthma. Bacterial, viral, fungal, and parasitic infections have each been examined and provide a framework for these novel concepts.

摘要

感染与过敏性气道疾病之间的关系早已得到认可,并且已有许多相关的综述文章。然而,过去 3 年发表的临床和基础科学研究为感染与过敏之间的关系提供了新的见解。在本次综述中,我们重点关注这些最新的研究,这些研究探讨了感染在哮喘的发生、维持和恶化中的作用。细菌、病毒、真菌和寄生虫感染都已被研究,并为这些新的概念提供了框架。

相似文献

1
Infections and asthma: new insights into old ideas.感染与哮喘:旧观念的新认识。
Clin Exp Allergy. 2010 Aug;40(8):1142-54. doi: 10.1111/j.1365-2222.2010.03563.x.
2
Whole-cell pertussis vaccine protects against Bordetella pertussis exacerbation of allergic asthma.全细胞百日咳疫苗可预防百日咳博德特氏菌加重过敏性哮喘。
Immunol Lett. 2005 Feb 15;97(1):91-100. doi: 10.1016/j.imlet.2004.10.011.
3
Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology.早期衣原体肺部感染通过免疫病理学的年龄依赖性差异增强过敏性气道疾病。
J Allergy Clin Immunol. 2010 Mar;125(3):617-25, 625.e1-625.e6. doi: 10.1016/j.jaci.2009.10.018. Epub 2010 Feb 1.
4
Role of atypical bacterial infection of the lung in predisposition/protection of asthma.肺部非典型细菌感染在哮喘易感性/保护中的作用。
Pharmacol Ther. 2004 Mar;101(3):193-210. doi: 10.1016/j.pharmthera.2003.10.007.
5
Influences of the microbiome on the early origins of allergic asthma.微生物组对过敏性哮喘早期发病的影响。
Ann Am Thorac Soc. 2013 Dec;10 Suppl:S165-9. doi: 10.1513/AnnalsATS.201305-118AW.
6
Induction, exacerbation and inhibition of allergic and autoimmune diseases by infection.感染对过敏性和自身免疫性疾病的诱导、加重及抑制作用。
Trends Immunol. 2005 May;26(5):260-7. doi: 10.1016/j.it.2005.03.009.
7
Atopic disease and its determinants -- a focus on the potential role of childhood infection.特应性疾病及其决定因素——聚焦儿童期感染的潜在作用。
Clin Exp Allergy. 2004 Aug;34(8):1184-91. doi: 10.1111/j.1365-2222.2004.02016.x.
8
Childhood asthma after bacterial colonization of the airway in neonates.新生儿气道细菌定植后的儿童哮喘。
N Engl J Med. 2007 Oct 11;357(15):1487-95. doi: 10.1056/NEJMoa052632.
9
Chlamydophila (Chlamydia) pneumoniae serology and asthma in adults: a longitudinal analysis.成人肺炎衣原体(衣原体)血清学与哮喘:一项纵向分析
J Allergy Clin Immunol. 2005 Nov;116(5):1123-8. doi: 10.1016/j.jaci.2005.08.030. Epub 2005 Oct 3.
10
Infections and asthma.感染与哮喘。
Clin Chest Med. 2006 Mar;27(1):87-98, vi. doi: 10.1016/j.ccm.2005.10.004.

引用本文的文献

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Helicobacter pylori infection increases the risk of adult-onset asthma: a nationwide cohort study.幽门螺杆菌感染增加成人哮喘发病风险:一项全国性队列研究。
Eur J Clin Microbiol Infect Dis. 2017 Sep;36(9):1587-1594. doi: 10.1007/s10096-017-2972-1. Epub 2017 Apr 8.
2
25-Hydroxyvitamin D3-deficiency enhances oxidative stress and corticosteroid resistance in severe asthma exacerbation.25-羟基维生素D3缺乏会加重严重哮喘发作时的氧化应激和皮质类固醇抵抗。
PLoS One. 2014 Nov 7;9(11):e111599. doi: 10.1371/journal.pone.0111599. eCollection 2014.
3
Inflammation and infections in asthma.
哮喘中的炎症与感染
Clin Respir J. 2015 Jul;9(3):257-69. doi: 10.1111/crj.12135. Epub 2014 May 15.
4
Otitis media in infancy and the development of asthma and atopic disease.婴幼儿中耳炎与哮喘和特应性疾病的发展。
Curr Allergy Asthma Rep. 2012 Dec;12(6):547-50. doi: 10.1007/s11882-012-0308-x.
5
Altered regulation of Toll-like receptor responses impairs antibacterial immunity in the allergic lung.改变 Toll 样受体反应的调节会损害过敏性肺部的抗菌免疫。
Mucosal Immunol. 2012 Sep;5(5):524-34. doi: 10.1038/mi.2012.28. Epub 2012 May 2.
6
IL-13 dampens human airway epithelial innate immunity through induction of IL-1 receptor-associated kinase M.IL-13 通过诱导 IL-1 受体相关激酶 M 抑制人呼吸道上皮固有免疫。
J Allergy Clin Immunol. 2012 Mar;129(3):825-833.e2. doi: 10.1016/j.jaci.2011.10.043. Epub 2011 Dec 9.
7
Pneumocystis elicits a STAT6-dependent, strain-specific innate immune response and airway hyperresponsiveness.卡氏肺孢子菌引发依赖 STAT6 的、菌株特异性的固有免疫应答和气道高反应性。
Am J Respir Cell Mol Biol. 2012 Mar;46(3):290-8. doi: 10.1165/rcmb.2011-0154OC. Epub 2011 Sep 29.
8
Up-regulation of MUC18 in airway epithelial cells by IL-13: implications in bacterial adherence.IL-13 上调气道上皮细胞中 MUC18 的表达:对细菌黏附的影响。
Am J Respir Cell Mol Biol. 2011 May;44(5):606-13. doi: 10.1165/rcmb.2010-0384OC. Epub 2011 Jan 14.