University of Texas at Austin, Austin, TX 78712, USA.
J Pers. 2010 Oct;78(5):1497-528. doi: 10.1111/j.1467-6494.2010.00659.x. Epub 2010 Jul 21.
Low sensation seekers are theorized to avoid risk more often because risk is emotionally more costly for them (in comparison to high sensation seekers). Therefore, individual differences in sensation seeking should predict differences in risk task-induced cortisol changes. Furthermore, the neural mediation that accounts for the relation between sensation seeking and cortisol changes has not been studied. The current study tested whether individual differences in sensation seeking predicted cortisol changes in relation to a risk task and whether this relation was mediated by frontal lobe activation. Participants (N=17) who varied in sensation seeking completed an fMRI study in which they rated the likelihood they would take various risks. Cortisol was measured from saliva samples collected prior to and after the fMRI procedure. The findings show that low sensation seekers showed the greatest rise in cortisol after the risk procedure, and this relation was partially mediated by increased orbitofrontal cortex activity.
低感觉寻求者被认为更频繁地避免风险，因为与高感觉寻求者相比，风险对他们的情感成本更高。因此，感觉寻求的个体差异应该预测风险任务引起的皮质醇变化的差异。此外，还没有研究感觉寻求与皮质醇变化之间关系的神经中介。本研究测试了感觉寻求的个体差异是否可以预测与风险任务相关的皮质醇变化，以及这种关系是否受到额叶激活的中介。参与者（N=17）在感觉寻求方面存在差异，他们完成了一项 fMRI 研究，在该研究中他们对自己愿意承担各种风险的可能性进行了评分。皮质醇是从 fMRI 程序前后采集的唾液样本中测量的。研究结果表明，低感觉寻求者在风险程序后皮质醇升高幅度最大，而这种关系部分是由眶额皮层活动增加介导的。
