Stergiopulos N, Young D F, Rogge T R
Biomedical Engineering Program, Iowa State University, Ames 50011.
Biomed Sci Instrum. 1991;27:93-104.
A computer model for simulating pressure and flow propagation in the human arterial system is developed. The model is based on the one-dimensional flow equations and includes non-linearities arising from geometry and material properties. Fifty five arterial segments, representing the various major arteries, are combined to form the model of the arterial system. Particular attention is paid to the development of peripheral pressure and flow pulses under normal flow conditions and under conditions of arterial disease. Cases investigated include arteriosclerosis and hypertension as well as the presence of single or multiple vascular occlusions. Results demonstrate that the model is capable of simulating arterial flow in a satisfactory manner.
开发了一种用于模拟人体动脉系统中压力和血流传播的计算机模型。该模型基于一维流动方程，并包含由几何形状和材料特性引起的非线性。代表各种主要动脉的55个动脉段被组合起来形成动脉系统模型。特别关注正常血流条件下以及动脉疾病条件下外周压力和血流脉冲的发展。所研究的病例包括动脉硬化、高血压以及存在单个或多个血管闭塞的情况。结果表明，该模型能够以令人满意的方式模拟动脉血流。
