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Lambert-Eaton 肌无力综合征导致纵隔镜活检后持续性神经肌肉无力-1 例报告。

Lambert-Eaton myasthenic syndrome as a cause of persistent neuromuscular weakness after a mediastinoscopic biopsy -A case report-.

机构信息

Department of Anesthesiology and Pain Medicine, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea.

出版信息

Korean J Anesthesiol. 2010 Jul;59(1):45-8. doi: 10.4097/kjae.2010.59.1.45. Epub 2010 Jul 21.

DOI:10.4097/kjae.2010.59.1.45
PMID:20651998
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2908227/
Abstract

There are many causes of prolonged postoperative muscle weakness, including drugs, residual anesthetics, cerebrovascular events, electrolyte imbalance, hypothermia, and neuromuscular disease. Neuromuscular diseases are relatively rare, with the most common being myasthenia gravis and Lambert-Eaton myasthenic syndrome (LEMS). We report an unusual case in which a patient who was given a muscle relaxant during mediastinoscopy developed postoperative muscle weakness that was ultimately diagnosed as secondary to LEMS.

摘要

术后肌肉无力的原因很多,包括药物、残留的麻醉剂、脑血管事件、电解质失衡、低体温和神经肌肉疾病。神经肌肉疾病相对少见,最常见的是重症肌无力和 Lambert-Eaton 肌无力综合征(LEMS)。我们报告了一例不常见的病例,患者在纵隔镜检查期间使用了肌肉松弛剂,随后出现术后肌肉无力,最终被诊断为继发于 LEMS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a8a/2908227/1b5989a3837d/kjae-59-45-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a8a/2908227/1b5989a3837d/kjae-59-45-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a8a/2908227/1b5989a3837d/kjae-59-45-g001.jpg

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本文引用的文献

1
Lambert-eaton myasthenic syndrome. Lambert-Eaton 肌无力综合征。
Curr Treat Options Neurol. 2009 Mar;11(2):77-84. doi: 10.1007/s11940-009-0010-z.
2
A diagnostic and management dilemma: combined paraneoplastic myasthenia gravis and Lambert-Eaton myasthenic syndrome presenting as acute respiratory failure.一个诊断与管理的难题:合并副肿瘤性重症肌无力和兰伯特-伊顿肌无力综合征并表现为急性呼吸衰竭
Neurologist. 2006 Nov;12(6):322-6. doi: 10.1097/01.nrl.0000250949.88356.22.
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Myasthenia gravis: myasthenia vs. cholinergic crisis.重症肌无力:肌无力与胆碱能危象。
Pediatr Emerg Care. 2005 Aug;21(8):546-8; quiz 549-51. doi: 10.1097/01.pec.0000173353.76142.81.
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New onset Lambert-Eaton myasthenic syndrome as an unexpected cause of delayed recovery from general anesthesia after thyroidectomy.新发兰伯特-伊顿肌无力综合征是甲状腺切除术后全身麻醉恢复延迟的意外原因。
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[Lambert-Eaton myasthenic syndrome with acute respiratory failure associated with small cell lung cancer].[伴急性呼吸衰竭的兰伯特-伊顿肌无力综合征与小细胞肺癌相关]
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Treatment for Lambert-Eaton myasthenic syndrome.兰伯特-伊顿肌无力综合征的治疗。
Cochrane Database Syst Rev. 2003(2):CD003279. doi: 10.1002/14651858.CD003279.
9
Paraneoplastic syndromes associated with lung cancer: a unique case of concomitant subacute cerebellar degeneration and Lambert-Eaton myasthenic syndrome.与肺癌相关的副肿瘤综合征:一例同时合并亚急性小脑变性和兰伯特-伊顿肌无力综合征的独特病例。
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Calcium channels in neurological disease.神经疾病中的钙通道
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