重症肌无力和 Lambert-Eaton 肌无力综合征的治疗进展。
Update in the Management of Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome.
机构信息
Clinical Neurology, Physical Medical Rehabilitation, Indiana University School of Medicine, Indiana University Health, Indianapolis, IN, USA.
Neurology Department, Indiana University School of Medicine, Indiana University Health, Indianapolis, Indiana, USA.
出版信息
Neurol Clin. 2021 Feb;39(1):133-146. doi: 10.1016/j.ncl.2020.09.007. Epub 2020 Nov 7.
Myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) are the most common disorders of neuromuscular transmission in clinical practice. Disorders of the neuromuscular junction (NMJ) are characterized by fluctuating and fatigable weakness and include autoimmune, toxic, and genetic conditions. Adults with NMJ disorders are most often antibody mediated, with MG being the most common, having a prevalence of approximately 1 in 10,000, and with women being affected about twice as often as men. This article focuses on advances in management of autoimmune MG and LEMS.
重症肌无力（MG）和 Lambert-Eaton 肌无力综合征（LEMS）是临床实践中最常见的神经肌肉传递障碍疾病。神经肌肉接头（NMJ）疾病的特征是波动性和易疲劳性无力，包括自身免疫性、中毒性和遗传性疾病。NMJ 疾病的成年人通常是抗体介导的，其中 MG 最为常见，患病率约为每 10000 人中有 1 例，女性的发病率约为男性的两倍。本文重点介绍了自身免疫性 MG 和 LEMS 的治疗进展。
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