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重组组织型纤溶酶原激活剂成功溶栓治疗大块肺栓塞-1 例报告。

Successful thrombolytic therapy with recombinant tissue-type plasminogen activator for massive pulmonary embolism -A case report-.

机构信息

Department of Anesthesiology and Pain Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.

出版信息

Korean J Anesthesiol. 2010 Jul;59(1):56-60. doi: 10.4097/kjae.2010.59.1.56. Epub 2010 Jul 21.

DOI:10.4097/kjae.2010.59.1.56
PMID:20652001
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2908230/
Abstract

Massive pulmonary embolism is associated with significant perioperative morbidity and mortality. We report here on a case of a 69-year-old man who suffered a massive pulmonary embolism with pulseless electrical activity during knee arthroscopic surgery. After a diagnosis was made by performing transthoracic echocardiography, the patient was treated with recombinant tissue-type plasminogen activator. The patient was transferred to the intensive care unit after his hemodynamic status improved. The patient went on to make a full cardiopulmonary recovery without any complications.

摘要

大面积肺栓塞与围手术期高发病率和死亡率密切相关。我们在此报告一例 69 岁男性患者,在膝关节镜手术中发生大面积肺栓塞合并无脉性电活动。经胸超声心动图检查后确诊,患者接受重组组织型纤溶酶原激活剂治疗。患者血流动力学状态改善后转入重症监护病房。患者心、肺功能完全恢复,无任何并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5565/2908230/69fbdb234ac2/kjae-59-56-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5565/2908230/79b62b5be175/kjae-59-56-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5565/2908230/74bd7e1517d7/kjae-59-56-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5565/2908230/69fbdb234ac2/kjae-59-56-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5565/2908230/79b62b5be175/kjae-59-56-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5565/2908230/74bd7e1517d7/kjae-59-56-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5565/2908230/69fbdb234ac2/kjae-59-56-g003.jpg

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Successful thrombolytic therapy with recombinant tissue-type plasminogen activator for massive pulmonary embolism -A case report-.重组组织型纤溶酶原激活剂成功溶栓治疗大块肺栓塞-1 例报告。
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引用本文的文献

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本文引用的文献

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Efficacy of thrombolytic agents in the treatment of pulmonary embolism.溶栓药物治疗肺栓塞的疗效
Eur Respir J. 2005 Nov;26(5):864-74. doi: 10.1183/09031936.05.00002505.
2
Pulmonary embolectomy for acute massive pulmonary embolism.急性大面积肺栓塞的肺动脉血栓切除术
Ann Thorac Surg. 2005 Apr;79(4):1240-4. doi: 10.1016/j.athoracsur.2004.08.081.
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British Thoracic Society guidelines for the management of suspected acute pulmonary embolism.英国胸科学会疑似急性肺栓塞管理指南。
Thorax. 2003 Jun;58(6):470-83. doi: 10.1136/thorax.58.6.470.
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Safety of thrombolysis during cardiopulmonary resuscitation.心肺复苏期间溶栓的安全性。
Drug Saf. 2003;26(6):367-79. doi: 10.2165/00002018-200326060-00001.
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Treatment of acute massive/submassive pulmonary embolism.急性大面积/次大面积肺栓塞的治疗
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Major pulmonary embolism: review of a pathophysiologic approach to the golden hour of hemodynamically significant pulmonary embolism.大面积肺栓塞:血流动力学显著的肺栓塞黄金救治时段的病理生理学方法综述
Chest. 2002 Mar;121(3):877-905. doi: 10.1378/chest.121.3.877.
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Alteplase as an alternative to urokinase. Advisory Panel on Catheter-Directed Thrombolytic Therapy.阿替普酶作为尿激酶的替代药物。导管定向溶栓治疗咨询小组。
J Vasc Interv Radiol. 2000 Mar;11(3):279-87. doi: 10.1016/s1051-0443(07)61418-3.
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The urgent pulmonary embolectomy: mechanical resuscitation in the operating theatre determines the outcome.急诊肺动脉血栓切除术:手术室中的机械复苏决定预后。
Thorac Cardiovasc Surg. 1999 Feb;47(1):5-8. doi: 10.1055/s-2007-1013099.
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Incidence and predictors of major hemorrhagic complications from thrombolytic therapy in patients with massive pulmonary embolism.
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Thrombolytic therapy for pulmonary embolism. Frequency of intracranial hemorrhage and associated risk factors.肺栓塞的溶栓治疗。颅内出血的发生率及相关危险因素。
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