生物条形码树状 DNA 作为信号放大器，用于基于钌纳米粒子的超灵敏化学发光检测的癌细胞分析。
Bio-bar-code dendrimer-like DNA as signal amplifier for cancerous cells assay using ruthenium nanoparticle-based ultrasensitive chemiluminescence detection.
机构信息
Key Laboratory of Eco-chemical Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
出版信息
Chem Commun (Camb). 2010 Sep 7;46(33):6093-5. doi: 10.1039/c0cc01409e. Epub 2010 Jul 23.
PMID:20652188
Abstract
Bio-bar-code dendrimer-like DNA (bbc-DL-DNA) is employed as a label for the amplification assay of cancer cells in combination with the newly explored chemiluminescence (CL) system of luminol-H(2)O(2)-Ru(3+) and specificity of structure-switching aptamers selected by cell-based SELEX.
摘要
生物条形码树枝状 DNA（bbc-DL-DNA）被用作标签，与新探索的鲁米诺-H2O2-Ru（3+）化学发光（CL）系统结合，用于基于细胞的 SELEX 选择的结构切换适体的特异性，对癌细胞进行扩增检测。
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