Biomathematics and Statistics Scotland, Invergowrie, Dundee, DD2 5DA, UK.
Theor Appl Genet. 2010 Nov;121(8):1483-8. doi: 10.1007/s00122-010-1404-8. Epub 2010 Jul 23.
The first genetic linkage map of blackcurrant, published by Brennan et al. (Euphytica 161:19-34, 2008), identified regions where quantitative trait loci (QTLs) for some important traits were located. The analysis was complicated by the fact that the mapping population was found to contain two subgroups, with segregation ratios consistent with these being crossed and selfed offspring. The QTL analysis was based on the trait mean over 3 years and focused on the crossed offspring. Here we proposed a mixed model multi-environment approach for this population. The 3 years are considered as three separate environments, the data from both the selfed and crossed offspring are combined and different residual terms are explored to model the correlation between the years. This permits tests for interactions between the QTLs, the year and the type of offspring (selfed or crossed). This is applied to re-analyse two important traits, anthocyanin concentration and budbreak. Several additional QTLs were identified, some affecting the trait in both the selfed and crossed offspring, others in just one.
布伦南等人发表的黑加仑第一张遗传连锁图谱（Euphytica 161：19-34，2008）确定了一些重要性状的数量性状基因座（QTL）所在的区域。由于绘图群体被发现包含两个亚群，其分离比与杂交和自交后代一致，因此分析变得复杂。QTL 分析基于 3 年的性状平均值，并集中在杂交后代上。在这里，我们为该群体提出了一种混合模型多环境方法。这 3 年被视为三个独立的环境，将自交和杂交后代的数据合并，并探索不同的残差项来模拟年份之间的相关性。这允许对 QTL、年份和后代类型（自交或杂交）之间的相互作用进行检验。这应用于重新分析两个重要性状，花色苷浓度和芽休眠。鉴定出了几个额外的 QTL，其中一些影响自交和杂交后代的性状，其他则只影响一个。
