Department of Medicine, Tuen Mun Hospital, New Territories, Hong Kong.
Rheumatol Int. 2011 Feb;31(2):259-62. doi: 10.1007/s00296-010-1574-3. Epub 2010 Jul 23.
Erythema elevatum diutinum (EED) is a rare chronic form of leukocytoclastic vasculitis with unknown etiology. EED has been described in association with hematological malignancies, infections and a number of rheumatological diseases. We report a patient with systemic lupus erythematosus (SLE) who presented with intermittent attacks of tender nodules and plaques on the shins and ankles for 6 months. Skin biopsy confirmed the diagnosis of EED. Treatment with dapsone resulted in complete resolution of the skin lesions. EED is rarely reported in SLE, and its presentation and treatment is reviewed.
持久性隆起性红斑(EED)是一种罕见的慢性白细胞碎裂性血管炎,其病因不明。EED 已被描述与血液系统恶性肿瘤、感染和许多风湿性疾病有关。我们报告了 1 例系统性红斑狼疮(SLE)患者,其小腿和脚踝间歇性出现触痛性结节和斑块 6 个月。皮肤活检证实了 EED 的诊断。用氨苯砜治疗后皮肤病变完全消退。EED 在 SLE 中很少见,我们对其表现和治疗进行了回顾。