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绿茶提取物——专利及用途多样性

Green tea extract-patents and diversity of uses.

作者信息

Saito Samuel T, Gosmann Grace, Pungartnik Cristina, Brendel Martin

机构信息

Programa de Pós-Graduação em Genética e Biologia Molecular, Universidade Estadual de Santa Cruz (UESC), Ilhéus, BA, Brazil.

出版信息

Recent Pat Food Nutr Agric. 2009 Nov;1(3):203-15. doi: 10.2174/2212798410901030203.

DOI:10.2174/2212798410901030203
PMID:20653541
Abstract

Green tea is one of the most consumed beverages in the world. Presently, Camellia sinensis has become a source not only for the development of several food extracts but also nutraceutical, cosmetic and medicinal purposes. The technology developed to produce these extracts aims to improve the organoleptic characteristics of the products as taste and smell, and their shelf life. But it also searches to demonstrate some medicinal attributes like antioxidant, anti-aging, anti-tumor and anti-viral activities in relation to the chemical composition of the green tea catechins, especially (-)-epigallocatechin gallate (EGCG). The target of this review is to present the various patents related to the extraction methods and their claims, and to discuss the evidence found in the literature about the pharmacological activities of green tea. It summarizes the recent progress in technology to obtain the green tea extract and in clinical studies on its applications. Health-promoting products and disease-preventing applications of green tea extract or compounds isolated from it also take part of this text.

摘要

绿茶是世界上消费最为广泛的饮品之一。目前,茶树不仅已成为多种食品提取物的来源,还用于营养保健品、化妆品及医药用途。开发生产这些提取物的技术旨在改善产品的感官特性,如味道和气味,以及延长其保质期。此外,该技术还试图证明绿茶儿茶素的化学成分,特别是(-)-表没食子儿茶素没食子酸酯(EGCG)所具有的一些药用特性,如抗氧化、抗衰老、抗肿瘤和抗病毒活性。本综述的目的是介绍与提取方法及其权利要求相关的各种专利,并讨论文献中关于绿茶药理活性的证据。它总结了获取绿茶提取物的技术以及其应用的临床研究方面的最新进展。绿茶提取物或从中分离出的化合物的健康促进产品及疾病预防应用也包含在本文中。

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Green tea extract-patents and diversity of uses.绿茶提取物——专利及用途多样性
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Bioavailability of Epigallocatechin Gallate Administered With Different Nutritional Strategies in Healthy Volunteers.不同营养策略下健康志愿者摄入表没食子儿没食子酸酯的生物利用度
Antioxidants (Basel). 2020 May 19;9(5):440. doi: 10.3390/antiox9050440.
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Oxidative stability of lipid fractions of sponge-fat cakes after green tea extracts application.
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Formulation and characterization of EGCG for the treatment of superficial bladder cancer.表没食子儿茶素没食子酸酯治疗浅表性膀胱癌的制剂及特性研究。
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