Anfossi Laura, Baggiani Claudio, Giovannoli Cristina, Giraudi Gianfranco
Department of Analytical Chemistry, University of Turin, Torino, Italy.
Recent Pat Food Nutr Agric. 2010 Jun;2(2):140-53. doi: 10.2174/2212798411002020140.
Mycotoxins are toxic compounds produced by various moulds, which can affect a variety of crops. Due to their high toxicity and wide diffusion, mycotoxins constitute a severe risk for human health, therefore maximum tolerance levels in food and feed products have been set up all over the world and analytical controls are mandatory for many commodities. Despite validated analytical methods for assessing mycotoxin contamination already existing, a number of papers describing new methods of extraction, identification or measurement appear daily in literature. Nevertheless, the extraction and determination of such contaminants in food and feed is a topic of constant and increasing interest, as also attested by the number of related patents which have been applied for in the last few years. Scientific papers dealing with mycotoxin occurrence, potential risk and determination have recently been reviewed. Nevertheless, the objective of this review is to focus on patent activity rather than on the scientific breakthroughs on this subject. Therefore, the most recent patents regarding the whole analytical protocol to measure mycotoxins in food, starting from 2006 to date are presented and discussed. The possibility of a technology transfer for the various innovations presented is also discussed as are future developments in the field.
霉菌毒素是由各种霉菌产生的有毒化合物，可影响多种农作物。由于其高毒性和广泛传播，霉菌毒素对人类健康构成严重风险，因此世界各地都制定了食品和饲料产品中的最大耐受水平，并且对许多商品进行强制性分析控制。尽管已经存在用于评估霉菌毒素污染的经过验证的分析方法，但文献中每天仍有许多论文描述新的提取、鉴定或测量方法。然而，食品和饲料中此类污染物的提取和测定一直是一个不断受到关注且关注度日益增加的话题，过去几年申请的相关专利数量也证明了这一点。最近对涉及霉菌毒素的存在、潜在风险和测定的科学论文进行了综述。然而，本综述的目的是关注专利活动，而不是该主题的科学突破。因此，本文展示并讨论了自2006年至今关于食品中霉菌毒素测量整个分析方案的最新专利。还讨论了所提出的各种创新技术转让的可能性以及该领域的未来发展。
