Tang Xia-jing, Yao Ke, Xu Wen, Shentu Xing-chao, Chen Pei-qing
Eye Center, Affiliated Second Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.
Zhonghua Yan Ke Za Zhi. 2010 Apr;46(4):328-31.
To compare spherical aberration, visual quality and apparent accommodation between pseudophakic patients with an aberration-free aspheric intraocular lens (IOL) and patients with a spherical IOL.
A prospective study of 130 consecutive cases (132 eyes) was conducted. All cataract patients underwent phacoemulsification were randomized to receive an aberration-free aspheric IOL (Akreos AO, Bausch & Lomb) or a spherical IOL (KS-1, Cannon Staar). Spherical aberration of total eye, best corrected visual acuity (BCVA), near visual acuity (NVA), contrast sensitivity, glare sensitivity and apparent accommodation were measured. Data were analyzed using chi-square test and independent t-test.
The mean spherical aberration in eyes with a Tecnis IOL [(0.141 +/- 0.070) microm] was significantly lower than that of eyes with a spherical IOL [(0.210 +/- 0.108) microm; t = 4.365, P = 0.000]. In addition, Akreos AO IOL provided a better contrast sensitivity at 2.5 degrees visual angle (30.62 +/- 12.50 vs. 25.92 +/- 7.36; t = 2.606, P = 0.010), and improved glare sensitivity at 4.0 degrees (31.25 +/- 8.65 vs. 26.70 +/- 7.98; t = 3.116, P = 0.002), 2.5 degrees (26.35 +/- 8.72 vs. 22.43 +/- 7.35; t = 2.772, P = 0.006) and 1.6 degrees (12.35 +/- 4.01 vs. 9.82 +/- 4.12; t = 3.553, P = 0.001) visual angles. The difference of BCVA, NVA and apparent accommodation between these two groups was not statistically significant.
The present results demonstrated that an aberration-free aspheric IOL, Akreos AO, may reduce the spherical aberration and improve visual performance of pseudophakic eyes and without negative influence on apparent accommodation as compare to conventional spherical IOL.
比较植入无像差非球面人工晶状体（IOL）的假晶状体眼患者与植入球面IOL的患者之间的球差、视觉质量和表观调节。
对连续130例（132只眼）进行前瞻性研究。所有接受白内障超声乳化术的患者被随机分配接受无像差非球面IOL（爱尔康AO，博士伦公司）或球面IOL（KS-1，佳能斯塔公司）。测量全眼的球差、最佳矫正视力（BCVA）、近视力（NVA）、对比敏感度、眩光敏感度和表观调节。使用卡方检验和独立t检验分析数据。
植入Tecnis IOL的眼的平均球差[（0.141±0.070）μm]显著低于植入球面IOL的眼[（0.210±0.108）μm；t = 4.365，P = 0.000]。此外，爱尔康AO IOL在2.5度视角下提供了更好的对比敏感度（30.62±12.50对25.92±7.36；t = 2.606，P = 0.010），并在4.0度（31.25±8.65对26.70±7.98；t = 3.116，P = 0.002）、2.5度（26.35±8.72对22.43±7.35；t = 2.772，P = 0.006）和1.6度（12.35±4.01对9.82±4.12；t = 3.553，P = 0.001）视角下改善了眩光敏感度。两组之间的BCVA、NVA和表观调节差异无统计学意义。
目前的结果表明，与传统的球面IOL相比，无像差非球面IOL爱尔康AO可能会降低球差并改善假晶状体眼的视觉性能，且对表观调节无负面影响。
