Shentu Xingchao, Tang Xiajing, Yao Ke
Eye Center, Affiliated Second Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Clin Exp Ophthalmol. 2008 Oct;36(7):620-4. doi: 10.1111/j.1442-9071.2008.01856.x.
To compare spherical aberration, visual performance and pseudoaccommodation in pseudophakic eyes implanted with aspheric intraocular lenses (IOLs) of Tecnis Z9001 with negative spherical aberration (AMO Inc.), aspheric aberration-free IOLs of Akreos AO (Bausch & Lomb Inc.) and spherical IOLs of KS-1 (Cannon Staar Inc.).
A total of 196 patients presenting for cataract surgery were randomly assigned to receive one of three types of IOLs in one eye. Spherical aberration, best-corrected far visual acuity (BCFVA), distance corrected near visual acuity (DCNVA), contrast sensitivity, glare sensitivity and pseudoaccommodation were measured and compared 3 months postoperatively.
At 3 months postoperatively, the mean spherical aberration Z(4,0) for 5 mm pupil size in eyes with Tecnis Z9001 IOLs, Akreos AO IOLs, and KS-1 IOLs were 0.022 +/- 0.071 microm, 0.141 +/- 0.070 microm and 0.210 +/- 0.108 microm, respectively (P < 0.001), and significant difference was also found in two aspheric IOLs (P < 0.001). Compared with spherical KS-1 IOLs, Tecnis Z9001 IOLs significantly improved the contrast sensitivity at 4.0 degrees, 2.5 degrees visual angle and glare sensitivity at 4.0 degrees, 2.5 degrees, 2.0 degrees, 1.6 degrees visual angle, Akreos AO IOLs significantly improved contrast sensitivity at 2.5 degrees and glare sensitivity at 4.0 degrees, 2.5 degrees, 2.0 degrees, but no difference statistically significance were found between two aspheric IOLs at any visual angle. In addition, there was no significant difference among three IOLs regarding BCFVA, DCNVA and pseudoaccommodation.
All the studied IOLs can provide good visual acuity. Compared with spherical IOLs, both aspheric IOLs can significantly decrease spherical aberration and improve visual performance without the reduction of pseudoaccommodation amplitude.
比较植入具有负球差的Tecnis Z9001非球面人工晶状体（AMO公司）、Akreos AO无球差人工晶状体（博士伦公司）和KS-1球面人工晶状体（佳能斯塔公司）的人工晶状体眼的球差、视觉性能和拟调节。
总共196例白内障手术患者被随机分配，一只眼植入三种类型人工晶状体中的一种。在术后3个月测量并比较球差、最佳矫正远视力（BCFVA）、距离矫正近视力（DCNVA）、对比敏感度、眩光敏感度和拟调节。
术后3个月，植入Tecnis Z9001人工晶状体、Akreos AO人工晶状体和KS-1人工晶状体的眼睛在5mm瞳孔大小时的平均球差Z(4,0)分别为0.022±0.071μm、0.141±0.070μm和0.210±0.108μm（P<0.001），两种非球面人工晶状体之间也存在显著差异（P<0.001）。与球面KS-1人工晶状体相比，Tecnis Z9001人工晶状体显著提高了4.0°、2.5°视角下的对比敏感度以及4.0°、2.5°、2.0°、1.6°视角下的眩光敏感度，Akreos AO人工晶状体显著提高了2.5°视角下的对比敏感度以及4.0°、2.5°、2.0°视角下的眩光敏感度，但两种非球面人工晶状体在任何视角下均未发现统计学上的显著差异。此外，三种人工晶状体在BCFVA、DCNVA和拟调节方面无显著差异。
所有研究的人工晶状体都能提供良好的视力。与球面人工晶状体相比，两种非球面人工晶状体均可显著降低球差并改善视觉性能，且不降低拟调节幅度。
