钙与能量：既要蛋糕，又要吃它？
Calcium and energy: making the cake and eating it too?
机构信息
Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 92105, USA.
出版信息
Cell. 2010 Jul 23;142(2):200-2. doi: 10.1016/j.cell.2010.07.007.
PMID:20655464
Abstract
Mitochondrial calcium ions promote a number of events that sustain ATP levels in the cell. Cardenas et al. (2010) now demonstrate that the inositol 1,4,5-triphosphate receptor at the endoplasmic reticulum constitutively provides calcium for mitochondria. In the absence of this calcium transfer, cells use autophagy to sustain survival.
摘要
线粒体钙离子促进了许多维持细胞内 ATP 水平的事件。Cardenas 等人（2010）现在证明内质网上的肌醇 1,4,5-三磷酸受体持续为线粒体提供钙离子。如果没有这种钙转移，细胞就会利用自噬来维持生存。
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