Department of Equine Sciences, Medicine Section, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Mol Genet Metab. 2010 Oct-Nov;101(2-3):289-91. doi: 10.1016/j.ymgme.2010.06.019. Epub 2010 Jul 23.
This case-series describes fourteen horses suspected of equine acquired multiple acyl-CoA dehydrogenase deficiency (MADD) also known as atypical myopathy of which seven cases were confirmed biochemically with all horses having had access to leaves of the Maple tree (Acer pseudoplatanus) covered with European tar spot (Rhytisma acerinum). Assessment of organic acids, glycine conjugates, and acylcarnitines in urine was regarded as gold standard in the biochemical diagnosis of equine acquired multiple acyl-CoA dehydrogenase deficiency.
本病例系列描述了 14 匹疑似马获得性多酰基辅酶 A 脱氢酶缺乏症（MADD）的马匹，也称为非典型肌病，其中 7 例通过生化方法得到证实，所有马匹都曾接触过覆盖有欧洲栎树叶炭疽菌（Rhytisma acerinum）的枫树（Acer pseudoplatanus）叶子。尿液中有机酸、甘氨酸缀合物和酰基肉碱的评估被认为是马获得性多酰基辅酶 A 脱氢酶缺乏症生化诊断的金标准。
