Pegasus Technologies, Burlington, Ontario, Canada.
Fertil Steril. 2011 Feb;95(2):542-7.e1-10. doi: 10.1016/j.fertnstert.2010.05.057. Epub 2010 Jul 24.
To present a report on assisted reproductive technologies (ART) cycles performed in 2007 in Canada and show trends in outcomes over time. This is the seventh annual report from the Canadian ART Register (CARTR).
Prospective cohort study.
Twenty-six of 26 ART centers in Canada.
PATIENT(S): Couples undergoing ART treatment in Canada during 2007.
INTERVENTION(S): ART treatments, including in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), and frozen embryo transfer (FET).
MAIN OUTCOME MEASURE(S): Clinical pregnancy, live-birth, and multiple-birth rates.
RESULT(S): A total of 13,482 ART cycles was reported to CARTR. In 8,972 IVF/ICSI cycles using the woman's own oocytes, per cycle started, the clinical pregnancy rate was 35.6% (41.0% per ET), and the live-birth rate was 28.6%; the multiple-birth rate per delivery was 30.2%, with a high-order multiple-birth rate of 1.1%. In 68% of cycles ICSI was performed. One or two embryos were transferred in 69% of cycles. In 404 IVF/ICSI cycles using donor oocytes, the clinical pregnancy rate was 44.6%, and the live-birth rate was 36.1%; the multiple-birth rate was 26.5%, with no triplet birth. In 3,224 FET cycles using the woman's own oocytes, the clinical pregnancy rate was 23.7%, and the live-birth rate was 17.8%; the multiple-birth rate was 24.1%, with a triplet birth rate of 0.2%. Birth outcomes were unknown for 2.0% of ongoing pregnancies.
CONCLUSION(S): For 2007, CARTR achieved 100% voluntary participation from Canadian ART centers for the fifth consecutive year. Clinical pregnancy and live-birth rates continued to increase in 2007 compared with previous years, with a decrease in high-order multiple births.
报告 2007 年加拿大实施的辅助生殖技术（ART）周期情况，并展示随时间推移的结果趋势。这是加拿大 ART 登记处（CARTR）的第七份年度报告。
前瞻性队列研究。
加拿大 26 个 ART 中心中的 26 个。
2007 年在加拿大接受 ART 治疗的夫妇。
ART 治疗，包括体外受精（IVF）、胞浆内精子注射（ICSI）和冷冻胚胎移植（FET）。
临床妊娠率、活产率和多胎率。
共向 CARTR 报告了 13482 个 ART 周期。在 8972 个使用患者自身卵子的 IVF/ICSI 周期中，每周期开始的临床妊娠率为 35.6%（每 ET 为 41.0%），活产率为 28.6%；每分娩的多胎率为 30.2%，多胎率为 1.1%。在 68%的周期中进行了 ICSI。在 69%的周期中移植了一个或两个胚胎。在 404 个使用供体卵子的 IVF/ICSI 周期中，临床妊娠率为 44.6%，活产率为 36.1%；多胎率为 26.5%，无三胞胎出生。在 3224 个使用患者自身卵子的 FET 周期中，临床妊娠率为 23.7%，活产率为 17.8%；多胎率为 24.1%，三胞胎出生率为 0.2%。2.0%的妊娠结局未知。
2007 年，CARTR 连续第五年实现了加拿大 ART 中心 100%的自愿参与。与前几年相比，2007 年临床妊娠率和活产率持续上升，高序多胎出生减少。
