Department of Nuclear Medicine, University Hospital Freiburg, Germany.
Radiother Oncol. 2010 Sep;96(3):308-10. doi: 10.1016/j.radonc.2010.07.004. Epub 2010 Jul 23.
Quantitative analysis can be included relatively easily in clinical PET-imaging protocols, but in order to obtain meaningful quantitative results one needs to follow a standardized protocol for image acquisition and data analysis. Important factors to consider are the calibration of the PET scanner, the radiotracer uptake time and the approach for definition of regions of interests. Using such standardized acquisition protocols quantitative parameters of tumor metabolism or receptor status can be derived from tracer kinetic analysis and simplified approaches such as calculation of standardized uptake values (SUVs).
定量分析可以相对容易地纳入临床 PET 成像方案中,但为了获得有意义的定量结果,需要遵循标准化的图像采集和数据分析方案。需要考虑的重要因素包括 PET 扫描仪的校准、放射性示踪剂摄取时间以及确定感兴趣区域的方法。通过使用这种标准化采集方案,可以从示踪剂动力学分析中得出肿瘤代谢或受体状态的定量参数,以及简化方法,如标准化摄取值(SUV)的计算。