Virology Division, Kimron Veterinary Institute, P.O. Box 12, Bet Dagan 50250, Israel.
Vet J. 2011 Jul;189(1):108-10. doi: 10.1016/j.tvjl.2010.06.007. Epub 2010 Jul 24.
This is the first report of an acute and fatal outbreak of bovine diarrhea virus (BVDV)-2 infection in Israel. The clinical presentation varied with the age of the affected animals with a bovine-respiratory-complex-like syndrome in young stock, and diarrhea and dysentery only in the lactating stock. Enteritis first appeared in one shed of post-parturient cows; it spread for 6 weeks, until at least 30% of the lactating stock contracted enteritis or dysentery. At the same time, dairy calves aged 10-90 days exhibited severe respiratory disease. Of 79 animals that died, 13/350 (3.7%) were adult lactating cows, and 66/1100 (6%) were young feedlot calves. Phylogenetic analysis of the isolated virus revealed a 95% identity with the corresponding genome parts of various BVDV type 2 sequences. The route of introduction of BVDV-2 into Israel could not be elucidated.
这是以色列首次报告牛腹泻病毒（BVDV）-2 感染的急性和致命性爆发。受感染动物的临床症状随年龄而变化，幼畜表现为类似于牛呼吸道综合征的症状，而哺乳期牛只则仅出现腹泻和痢疾。肠炎首先出现在一个分娩后的牛舍中；它传播了 6 周，直到至少 30%的哺乳期牛只感染了肠炎或痢疾。与此同时，10-90 天大的奶牛犊牛表现出严重的呼吸道疾病。在 79 头死亡的动物中，350 头成年哺乳期奶牛中有 13 头（3.7%），1100 头育肥犊牛中有 66 头（6%）。对分离病毒的系统进化分析显示，其与各种 BVDV 2 型序列的相应基因组部分具有 95%的同一性。BVDV-2 传入以色列的途径尚不清楚。
