André M, Boutroy M J, Bianchetti G, Vert P, Morselli P L
Service de Médecine Néonatale, Maternité Régionale A. Pinard, Nancy, France.
Eur J Clin Pharmacol. 1991;40(2):193-5. doi: 10.1007/BF00280077.
The attempt has been made to define the optimal dose regimen of clonazepam in newborns suffering from neonatal convulsions. Results obtained from 22 patients (GA 28-41 weeks; PNA 4 h to 23 days) indicated that a dose of 0.1 mg/kg every 24 h was satisfactory in the majority of the patients. It is recommended as a starting regimen.
已尝试确定氯硝西泮在患有新生儿惊厥的新生儿中的最佳给药方案。对22例患者(胎龄28 - 41周;出生后年龄4小时至23天)的研究结果表明,大多数患者每24小时给予0.1 mg/kg的剂量是令人满意的。建议将此作为起始方案。