Reddy B V R, Sridhar G R, Anuradha C H, Chandrasekhar P, Lingamaneni K P
Department of Oral Pathology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India.
Indian J Dent Res. 2010 Apr-Jun;21(2):302-5. doi: 10.4103/0970-9290.66644.
Primary mucosal malignant melanoma of the oral cavity is a rare tumor. It accounts for only 0.2-8% of all malignant melanomas. This malignancy commonly affects male subjects and is more frequently seen on the hard palate and maxillary gingiva. The peak age for diagnosis of oral melanoma is between 55 and 65 years. A biopsy is required to establish a diagnosis. Ablative surgery with tumor-free margins remains the treatment of choice. It has a much poorer prognosis than its counterpart on the skin. Here, we present a case of malignant melanoma of the mandibular lingual gingiva in a 55-year-old male patient. Immunohistochemistry and special stains were conducted for confirmatory diagnosis.
口腔原发性黏膜恶性黑色素瘤是一种罕见肿瘤。它仅占所有恶性黑色素瘤的0.2 - 8%。这种恶性肿瘤通常累及男性患者,更常见于硬腭和上颌牙龈。口腔黑色素瘤的诊断高峰年龄在55至65岁之间。需要进行活检以确诊。采用切缘无瘤的切除手术仍是首选治疗方法。其预后比皮肤恶性黑色素瘤差得多。在此,我们报告一例55岁男性患者下颌舌侧牙龈恶性黑色素瘤的病例。进行了免疫组织化学和特殊染色以确诊。