Department of Dermatology, Sassoon Hospital, Pune-1, Maharashtra, India.
Indian J Dermatol Venereol Leprol. 2010 Jul-Aug;76(4):404-7. doi: 10.4103/0378-6323.66598.
A 50-year-old male presented with fever, joint pain and skin lesions since eight months. Examination showed multiple papules and nodules with periarticular predisposition. Swelling of knees and elbows with flexion deformity of distal interphalangeal joints was present. Investigations revealed anemia and raised ESR. Histopathology was pathognomonic of multicentric reticulohistiocytosis. Patient was treated with bisphosphonates along with systemic steroids and methotrexate to which he responded well.
一位 50 岁男性，出现发热、关节痛和皮肤损伤，已有八个月。检查显示多发性丘疹和结节，有向关节周围分布的倾向。存在膝关节和肘关节肿胀，伴有远端指间关节的屈曲畸形。检查发现贫血和血沉升高。组织病理学表现为多中心性网状组织细胞增生症的特征性改变。患者接受双膦酸盐治疗，同时还使用全身类固醇和甲氨蝶呤治疗，反应良好。
