多中心性网状组织细胞增生症
Multicentric reticulohistiocytosis.
作者信息
Shah Sejal P, Shah Aditya M, Prajapati Sachin M, Bilimoria Freny E
机构信息
Department of Dermatology, SBKS Medical College and Research Centre, Sumandeep Vidyapeeth, Pipariya, Waghodia, Baroda, Gujarat, India.
出版信息
Indian Dermatol Online J. 2011 Jul;2(2):85-7. doi: 10.4103/2229-5178.85998.
Multicentric reticulohistiocytosis is a rare systemic granulomatous disease of an unknown cause, characterized by distinct histopathology. The skin, mucosa, synovial, bone, and internal organs may be involved. Cutaneous nodules and distinctive arthritis are the most prominent clinical features. A 55-year-old female was referred from Orthopedic Outpatient Department, with multiple, painful and tender nodules on the dorsum of her hands, forearms, elbows, back, and neck. The lesions were present predominantly around the joints with associated arthropathies. Smaller nodules were seen on the ear helices. There was no other clinically evident or investigative abnormality. A histopathological study confirmed the diagnosis of multicentric reticulohistiocytosis.
多中心网状组织细胞增生症是一种病因不明的罕见系统性肉芽肿性疾病，具有独特的组织病理学特征。皮肤、黏膜、滑膜、骨骼和内脏器官均可受累。皮肤结节和特征性关节炎是最突出的临床特征。一名55岁女性从骨科门诊转诊而来，其双手背、前臂、肘部、背部和颈部有多个疼痛性压痛结节。病变主要出现在关节周围并伴有关节病。耳轮上可见较小的结节。无其他临床明显异常或检查异常。组织病理学研究确诊为多中心网状组织细胞增生症。
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