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核心技术专利：CN118964589B侵权必究

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

University of Utah School of Medicine, Salt Lake City, Utah 84132, USA.

Curr Opin Support Palliat Care. 2010 Sep;4(3):195-9. doi: 10.1097/SPC.0b013e32833d3011.

PURPOSE OF REVIEW

Bone has always been considered a target organ for neoplastic disorder. This review analyzed the close interaction between bone microenvironment and paraproteinemias.

RECENT FINDINGS

Paraproteinemias are a group of disorders characterized by the presence of a monoclonal protein measured in the blood or urine. Paraproteinemias include nonmalignant B cell disorders such as monoclonal gammopathy of undetermined significance and malignant diseases as multiple myeloma. All these conditions are characterized by increased risk of osteoporosis/osteopenia, and in the setting of multiple myeloma can manifest with osteolytic pattern.

SUMMARY

This review focuses on the biological aspects of paraproteinemia and bone disease, and indicates possible new therapeutic interventions.

目的综述

骨骼一直被认为是肿瘤性疾病的靶器官。本综述分析了骨微环境与副蛋白之间的密切相互作用。

总结

本综述侧重于副蛋白血症和骨病的生物学方面，并指出可能的新的治疗干预措施。

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University of Utah School of Medicine, Salt Lake City, Utah 84132, USA.

Curr Opin Support Palliat Care. 2010 Sep;4(3):195-9. doi: 10.1097/SPC.0b013e32833d3011.

PURPOSE OF REVIEW

Bone has always been considered a target organ for neoplastic disorder. This review analyzed the close interaction between bone microenvironment and paraproteinemias.