Robertson A J, Anderson J M, Brown R A, Slidders W, Beck J S
J Clin Pathol. 1978 May;31(5):469-74. doi: 10.1136/jcp.31.5.469.
Cerebral astrocytomas and undifferentiated gliomas were graded by (1) Kernohan classification on the basis of visual microscopy, and (2) optical density/area profiles obtained by automated densitometry with a Quantimet 720 image-analysing computer. In a retrospective study of 44 patients the Quantimet measurements seemed to give a more accurate assessment of prognosis than visual grading.