Department of Oral and Maxillofacial Surgery, University Clinical Centre, Ljubljana, Slovenia.
Int J Oral Maxillofac Implants. 2010 Jul-Aug;25(4):690-8.
To characterize the normal bacterial flora and evaluate the presence of periodontopathogenic bacteria around dental implants and to correlate them with the periodontal flora or, in completely edentulous patients, the alveolar gingival flora.
Clinical and radiographic parameters were recorded to exclude peri-implantitis in 34 partially edentulous and 19 completely edentulous patients. Partially edentulous patients were subdivided into two subgroups based on the depth of the periodontal pocket: ≤ 4 mm (n = 19) and > 4 mm (n = 15). Microbial samples were collected from peri-implant sulci, the deepest periodontal sulci, and, for completely edentulous patients, from the alveolar gingiva. Predominant aerobic bacteria were determined by microbiologic culturing, and multiplex polymerase chain reaction was used to detect five periodontopathogenic bacteria: Porphyromonas gingivalis, Tannerella forsythensis, Treponema denticola, Prevotella intermedia, and Actinobacillus actinomycetemcomitans.
In all the examined patients, oral streptococci were the most frequent aerobic peri-implant bacteria. The frequency of four periodontopathogenic bacteria in tooth sulci (A actino?mycetemcomitans, P gingivalis, T forsythensis, T denticola) was significantly higher around natural teeth with deeper periodontal pockets, but there was no significant difference in the frequency of the same bacteria in peri-implant sulci in the two partially edentulous subgroups. In contrast, there were no such bacteria in the peri-implant sulci or the alveolar gingiva of completely edentulous patients.
In healthy peri-implant sulci, oral streptococci constitute the predominant bacterial flora. In partially edentulous patients four periodontopathogenic bacteria were detected around implants, and none of these bacteria were found around implants in completely edentulous patients.
描述正常细菌菌群，并评估牙周致病菌在牙种植体周围的存在情况，并将其与牙周菌群相关联，或者在完全无牙患者中与牙槽牙龈菌群相关联。
记录了 34 名部分缺牙和 19 名完全无牙患者的临床和影像学参数，以排除种植体周围炎。部分缺牙患者根据牙周袋深度进一步分为两组：≤4mm（n=19）和>4mm（n=15）。从种植体周围沟、最深牙周袋以及完全无牙患者的牙槽牙龈采集微生物样本。通过微生物培养确定主要需氧菌，并用多重聚合酶链反应检测五种牙周致病菌：牙龈卟啉单胞菌、福赛坦纳氏菌、牙髓密螺旋体、中间普氏菌和伴放线放线杆菌。
在所有检查的患者中，口腔链球菌是最常见的需氧种植体周围细菌。在牙齿沟中，四种牙周致病菌（伴放线放线杆菌、牙龈卟啉单胞菌、福赛坦纳氏菌、牙髓密螺旋体）的频率在牙周袋较深的天然牙齿周围显著更高，但在两个部分缺牙亚组的种植体周围沟中，相同细菌的频率没有显著差异。相比之下，在完全无牙患者的种植体周围沟或牙槽牙龈中没有这些细菌。
在健康的种植体周围沟中，口腔链球菌构成主要的细菌菌群。在部分缺牙患者中，在种植体周围检测到四种牙周致病菌，而在完全无牙患者中未发现这些细菌。
