自体骨移植后 3 年的垂直骨嵴增加:可吸收屏障与钛增强屏障。一项随机对照临床试验。

Vertical ridge augmentation with autogenous bone grafts 3 years after loading: resorbable barriers versus titanium-reinforced barriers. A randomized controlled clinical trial.

机构信息

Oral and Maxillofacial Surgery, School of Dentistry, University of Manchester, United Kingdom.

出版信息

Int J Oral Maxillofac Implants. 2010 Jul-Aug;25(4):801-7.

DOI:
Abstract

PURPOSE

To compare the efficacy of two different techniques for vertical bone regeneration at implant placement with particulated autogenous bone at 3 years after loading: resorbable collagen barriers supported by osteosynthesis plates and nonresorbable titanium-reinforced expanded polytetrafluoroethylene barriers.

MATERIALS AND METHODS

Twenty-two partially edentulous patients requiring vertical bone augmentation were randomly allocated to two treatment groups, each composed of 11 patients. Prosthetic and implant failures, complications, the amount of vertically regenerated bone, and peri-implant marginal bone levels were recorded by independent and blinded assessors. The implant site requiring the most vertical bone regeneration was selected in each patient for bone level assessment. The follow-up time ranged from provisional loading to 3 years after loading. Analysis of covariance and paired t tests were conducted to compare means at the .05 level of significance.

RESULTS

No patient dropped out or was excluded at the 3-year follow-up. No prosthetic failures and no implant failures or complications occurred after loading. There was no statistically significant difference in bone loss between the two groups at either 1 year or 3 years. Both groups had gradually lost a statistically significant amount of peri-implant bone at 1 and 3 years (P < .05). After 3 years, patients treated with resorbable barriers had lost a mean of 0.55 mm of bone; patients who had received nonresorbable barriers showed a mean of 0.53 mm of bone loss.

CONCLUSIONS

Up to 3 years after implant loading, no failures or complications occurred and peri-implant marginal bone loss was minimal. Vertically regenerated bone can be successfully maintained after functional loading.

摘要

目的

比较两种不同技术在种植体植入时使用颗粒自体骨进行垂直骨再生的效果:可吸收胶原屏障联合骨内固定和不可吸收钛增强膨化聚四氟乙烯屏障。

材料与方法

22 名需要垂直骨增量的部分无牙颌患者随机分配到两组治疗组,每组 11 名患者。由独立和盲法评估者记录修复体和种植体失败、并发症、垂直再生骨量和种植体周缘骨水平。在每个患者中选择需要最大垂直骨再生的种植体部位进行骨水平评估。随访时间从临时负载到负载后 3 年。采用协方差分析和配对 t 检验在.05 水平比较均值。

结果

在 3 年随访时,无患者脱落或排除。负载后无修复体失败和种植体失败或并发症。两组在 1 年和 3 年均无统计学意义的骨丢失差异。两组在 1 年和 3 年均逐渐出现统计学意义的种植体周缘骨丢失(P <.05)。3 年后,使用可吸收屏障的患者平均骨丢失 0.55mm;接受不可吸收屏障的患者平均骨丢失 0.53mm。

结论

在种植体负载后 3 年内,未发生失败或并发症,种植体周缘骨丢失最小。垂直再生骨可在功能负载后成功维持。

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