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一项关于后牙区萎缩性下颌骨修复的随机对照试验的3年加载后报告:垂直骨增量后的短种植体还是长种植体?

A 3-year post-loading report of a randomised controlled trial on the rehabilitation of posterior atrophic mandibles: short implants or longer implants in vertically augmented bone?

作者信息

Esposito Marco, Cannizarro Gioacchino, Soardi Elisa, Pellegrino Gerardo, Pistilli Roberto, Felice Pietro

机构信息

Department of Biomaterials, Goteborg University, Sweden.

出版信息

Eur J Oral Implantol. 2011 Winter;4(4):301-11.

Abstract

OBJECTIVES

To evaluate whether 6.3 mm-long implants could be a suitable alternative to longer implants placed in vertically augmented atrophic posterior mandibles.

MATERIALS AND METHODS

Sixty partially edentulous patients having 7 to 8 mm of residual crestal height and at least 5.5 mm thickness measured on CT scans above the mandibular canal were randomised according to a parallel group design either to receive 1 to 3 submerged 6.3 mm-long implants or 9.3 mm or longer implants (30 patients per group) placed in vertically augmented bone. Bone was augmented with interpositional an organic bovine bone blocks covered by resorbable barriers. Grafts were left to heal for 5 months before implant placement. Four months later, provisional acrylic prostheses were delivered, and were then replaced after another 4 months by definitive metal-ceramic prostheses. Outcome measures were prosthesis and implant failures, complications, and radiographic peri-implant marginal bone level changes. All patients were followed up to 3 years after loading.

RESULTS

Four patients dropped out, two from each group. The augmentation procedure failed in two patients and only 6.3 mm-long implants could be inserted. There were no statistically significant differences for prosthesis and implant failures. Three prostheses could not be placed or had to be remade in the short implant group versus 4 prostheses in the augmented group. Two short implants failed versus 3 long implants, all in different patients. There were statistically significantly more complications in augmented patients (22 complications in 20 augmented patients versus 5 complications in 5 patients of the short implant group). Both groups gradually lost peri-implant bone in a statistically significant way at 4 months, and 1 and 3 years after loading. Three years after loading, patients of the short implant group lost an average of 1.24 mm of peri-implant bone compared with 1.76 mm in the long implant group. Short implants experienced statistically significantly less bone loss (0.52 mm; CI 95% 0.20 to 0.83, P = 0.002) than long implants.

CONCLUSIONS

When residual bone height over the mandibular canal is between 7 and 8 mm, 6.3 mm short implants could be an interesting alternative to vertical augmentation since the treatment is faster, cheaper and associated with less morbidity. Longer follow-ups are needed to confirm these results.

摘要

目的

评估6.3毫米长的种植体是否可作为垂直骨增量后的萎缩性下颌后牙区较长种植体的合适替代方案。

材料与方法

60例部分牙列缺损患者,在下颌管上方CT扫描测得剩余牙槽嵴高度为7至8毫米,厚度至少为5.5毫米,根据平行组设计随机分组,分别接受1至3枚6.3毫米长的潜入式种植体或9.3毫米及更长的种植体(每组30例患者),种植于垂直骨增量后的骨组织中。采用可吸收屏障覆盖的有机牛骨块进行骨增量。在种植体植入前,让骨块愈合5个月。4个月后,安装临时丙烯酸义齿,再过4个月后更换为最终的金属烤瓷义齿。观察指标包括义齿和种植体失败情况、并发症以及种植体周围边缘骨水平的影像学变化。所有患者在负重后随访3年。

结果

4例患者退出研究,每组各2例。2例患者的骨增量手术失败,仅能植入6.3毫米长的种植体。义齿和种植体失败情况无统计学显著差异。短种植体组有3例义齿无法安装或需重新制作,而骨增量组为4例。2枚短种植体失败,3枚长种植体失败,均发生在不同患者。骨增量患者的并发症在统计学上显著更多(20例骨增量患者出现22例并发症,而短种植体组5例患者出现5例并发症)。两组在负重后4个月、1年和3年时,种植体周围骨均以统计学显著方式逐渐吸收。负重3年后,短种植体组患者种植体周围骨平均吸收1.24毫米,长种植体组为1.76毫米。短种植体的骨吸收在统计学上显著少于长种植体(0.52毫米;95%可信区间0.20至0.83,P = 0.002)。

结论

当下颌管上方剩余骨高度在7至8毫米之间时,6.3毫米的短种植体可能是垂直骨增量的一个有吸引力的替代方案,因为该治疗更快、更便宜且发病率更低。需要更长时间的随访来证实这些结果。

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