Pathology Department, A. C. Camargo Hospital, Brazil.
Braz J Otorhinolaryngol. 2010 May-Jun;76(3):374-7. doi: 10.1590/S1808-86942010000300017.
Neck dissection is an integral part of head and neck tumors. Throughout its history, it has undergone changes looking for an improvement in functional outcome without loss of oncologic efficiency.
Demonstrate that the modified radical neck dissection have an oncologic results comparable to classical radical dissection.
We included patients with squamous cell carcinoma of the lower floor of the mouth and oropharynx, who underwent radical classic or modified neck dissection. We excluded from this analysis those patients who had undergone previous treatment or extended neck dissection.
Retrospective study, involving an institution.
We identified 481 patients who met the inclusion criteria, corresponding to 521 dissections. The average number of lymph nodes dissected was 44.92 (SD 16:45) lymph nodes to the RCT, 44.16 (SD 15.76) for the MRND + XI and 56.02 (SD 22.91) for the ECRM IJV + XI. The ANOVA indicated a statistically significant difference between groups (p<0.001). The type of neck dissection was not significant for regional recurrence or disease-specific survival.
The use of modified neck dissection has no significant impact on the pathological staging, disease-free survival or disease-specific survival.
证明改良根治性颈清扫术与经典根治性颈清扫术具有相似的肿瘤学结果。
我们纳入了接受根治性经典或改良颈清扫术的口腔底和口咽鳞状细胞癌患者。我们排除了先前接受过治疗或广泛颈清扫术的患者。
回顾性研究，涉及一个机构。
我们确定了 481 名符合纳入标准的患者，共进行了 521 次清扫术。平均清扫的淋巴结数为 44.92（SD 16:45）个淋巴结，RCT 为 44.16（SD 15.76）个淋巴结，MRND + XI 为 56.02（SD 22.91）个淋巴结，ECRM IJV + XI 为 56.02（SD 22.91）个淋巴结。方差分析表明组间存在统计学显著差异（p<0.001）。颈清扫术的类型与区域复发或疾病特异性生存率无关。
改良颈清扫术的应用对病理分期、无病生存率或疾病特异性生存率没有显著影响。
