Institute of Health Service Research, Peninsula College of Medicine & Dentistry, University of Exeter, Veysey Building, Salmon Pool Lane, Exeter, Devon EX2 4SG, UK.
Qual Life Res. 2011 Feb;20(1):57-67. doi: 10.1007/s11136-010-9717-2. Epub 2010 Jul 25.
To investigate for socially isolated older people, and older people at risk of social isolation: (1) health status and health-related quality of life (HRQL); (2) the relationship between social isolation and health status/HRQL; (3) the relationship between two alternative measures of health status/HRQL.
Older people at risk of social isolation (n = 393) completed the EQ-5D and the SF-12. Multiple regression analyses were performed to examine the relationship between levels of social isolation and health status/HRQL, controlling for demographic/clinical characteristics. The agreement between EQ-5D and SF-6D (SF-12) scores was explored using descriptive psychometric techniques.
Health status and health state values were much lower than UK general population age-matched norms. After controlling for depression, physical co-morbidities, age, gender, living alone status, employment and accommodation, social isolation was significantly associated, to a degree that was clinically relevant, with EQ-5D DSI, SF-6D (SF-12) and SF-12 MCS scores. The potential for ceiling effects on the EQ-5D with this population was identified.
This work highlights the burden that social isolation may have on the health and well-being of older people. The potential HRQL gains from addressing social isolation may be considerable, with those at risk of social isolation also a key target group.
调查社会孤立的老年人和有社会隔离风险的老年人：（1）健康状况和健康相关生活质量（HRQL）；（2）社会隔离与健康状况/HRQL 之间的关系；（3）两种替代健康状况/HRQL 衡量标准之间的关系。
有社会隔离风险的老年人（n=393）完成了 EQ-5D 和 SF-12。进行多元回归分析，以考察社会隔离程度与健康状况/HRQL 之间的关系，控制人口统计学/临床特征。使用描述性心理测量技术探讨 EQ-5D 和 SF-6D（SF-12）评分之间的一致性。
健康状况和健康状态值远低于英国普通人群年龄匹配的正常值。在控制抑郁、身体合并症、年龄、性别、独居状态、就业和住房后，社会隔离与 EQ-5D DSI、SF-6D（SF-12）和 SF-12 MCS 评分显著相关，程度上具有临床相关性。发现该人群的 EQ-5D 存在天花板效应的可能性。
这项工作强调了社会隔离可能对老年人的健康和福祉造成的负担。通过解决社会隔离问题，潜在的 HRQL 收益可能相当可观，有社会隔离风险的人群也是一个关键的目标群体。
