Walss Rodríguez R J, Chávez Chávez S L, Mora Villa R
División de Ginecología y Obstetricia, Centro Médico Nacional del IMSS de Torreón, Coah.
Ginecol Obstet Mex. 1991 Feb;59:46-9.
To evaluate intracervical PGE2 plus low dose oxytocin in the induction of cervical changes and labor, we studied 36 pregnant patients who had one of the following complications: Intrauterine death, anencephaly, gestational trophoblastic disease, missed abortion and PRM with pregnancy less than 28 weeks of gestational age. 200 mcgs of PGE2 were applied in the cervix, and immediately an oxytocin infusion was started at 2 mlU, the dose of oxytocin was increased in the arithmetic fashion until labor was started. The latency between the application of PGE2 and the beginning of labor was 3.57 +/- 3.29 h., between the beginning of labor and birth was 5.59 +/- 3.39 h. The cervix changed from a Bishop score of 2.1 +/- 1.5 to 6.2 +/- 1.8 (p less than 0.0001). The hospital stay was of 1.6 +/- 0.6 days. The secondary affects were minimal, and the births were all vaginal.
为评估宫颈内给予前列腺素E2（PGE2）加小剂量缩宫素在诱导宫颈变化和引产中的作用，我们研究了36例患有以下并发症之一的孕妇：宫内死亡、无脑儿、妊娠滋养细胞疾病、稽留流产以及孕周小于28周的胎膜早破。将200微克PGE2应用于宫颈，随后立即以2毫国际单位开始静脉滴注缩宫素，缩宫素剂量以算术方式增加直至引产开始。应用PGE2至引产开始的潜伏期为3.57±3.29小时，引产开始至分娩的时间为5.59±3.39小时。宫颈Bishop评分从2.1±1.5变为6.2±1.8（p＜0.0001）。住院时间为1.6±0.6天。次要影响极小，且所有分娩均为阴道分娩。
