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[口腔黏膜色素沉着病变的比色研究]

[A colorimetric study of pigmented lesions on oral mucosa].

作者信息

Suzuki Miho

机构信息

Section of Maxillofacial Surgery, Department of Maxillofacial Reconstruction and Function, Division of Maxillofacial and Neck Reconstruction, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University.

出版信息

Kokubyo Gakkai Zasshi. 2010 Jun;77(2):149-55.

Abstract

The purpose of this study is to state the clinical and colorimetric features of pigmented lesions on oral mucosa. Among 201 pigmented lesions on oral mucosa, there were 74 melanin pigmentations (36.9%), 72 exogenous pigmentations (35.8%), 28 pigmented nevi (13.9%), and 27 malignant melanomas (13.4%). Melanin pigmentations were found mainly on the gingiva and lip, exogenous pigmentations were on the gingiva, pigmented nevi were found on the buccal mucosa, and malignant melanomas were on the upper gingiva. Thirty-six pigmented lesions were measured by colorimeter, and each lesion was evaluated numerically using the CIE Lab* colorimetric system. The statistical significance was confirmed by Tukey's test and a p value <0.05 was assumed as a significant difference. The color distribution of melanin pigmentation and exogenous pigmentation and malignant melanoma were significantly lower than normal mucosa in L*. A statistical significance was found between each pigmented lesion and normal mucosa in a* and b*. Among malignant melanoma and melanin pigmentation or exogenous pigmentation, a statistical significance was found in a* and b*. The color difference between melanin pigmentation and malignant melanoma was significant. The color distribution is thought to be different in each pigmented lesion, and we suggest that it is useful to use colorimetric features to diagnose each pigmented lesion.

摘要

本研究的目的是阐述口腔黏膜色素沉着病变的临床及比色特征。在201例口腔黏膜色素沉着病变中,有74例黑色素沉着(36.9%),72例外源性色素沉着(35.8%),28例色素痣(13.9%),以及27例恶性黑色素瘤(13.4%)。黑色素沉着主要见于牙龈和唇部,外源性色素沉着见于牙龈,色素痣见于颊黏膜,恶性黑色素瘤见于上牙龈。用比色计测量了36例色素沉着病变,并使用CIE Lab比色系统对每个病变进行数值评估。通过Tukey检验确定统计学意义,p值<0.05被视为有显著差异。黑色素沉着、外源性色素沉着和恶性黑色素瘤的颜色分布在L值上显著低于正常黏膜。在a和b值方面,各色素沉着病变与正常黏膜之间存在统计学意义。在恶性黑色素瘤与黑色素沉着或外源性色素沉着之间,在a和b值上存在统计学意义。黑色素沉着与恶性黑色素瘤之间的颜色差异显著。认为各色素沉着病变的颜色分布有所不同,我们建议利用比色特征来诊断各色素沉着病变是有用的。

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