Rythén Marianne, Sabel Nina, Dietz Wolfram, Robertson Agneta, Norén Jörgen G
Department of Pedodontics, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
Eur J Oral Sci. 2010 Aug;118(4):389-95. doi: 10.1111/j.1600-0722.2010.00755.x.
Preterm children with very low birth weight suffer from several neonatal and postnatal complications that may affect the mineralization of teeth. Clinical and morphological studies have shown enamel aberrations in teeth from preterm children. In this study, the chemical composition in enamel and dentin was compared in primary teeth from preterm children and full-term children, and the relationship between the chemical composition and the morphological appearance was investigated. Enamel and dentin in 17 exfoliated primary teeth, from 14 children with a gestational age below 29 wk, were investigated and compared with 36 exfoliated primary teeth from full-term children, using X-ray microanalyses (XRMA). In comparison with the teeth from the controls, the teeth from preterm children had a higher relative value of carbon (C), a lower relative value of calcium (Ca), a lower ratio of calcium/phosphorus (Ca/P) and a lower ratio of Ca/C throughout the outer part of the enamel. In dentin, the relative values for P were higher, and Ca/P ratio was lower, at the dentin-pulp junction. The Ca/P ratio indicated normal hydroxyapatite in the crystals in enamel and dentin. The lower ratio of Ca/C in the bulk and outer part of the enamel indicated more porous enamel.
极低出生体重的早产儿会遭受多种新生儿期和出生后并发症，这些并发症可能影响牙齿矿化。临床和形态学研究已显示早产儿牙齿存在釉质异常。在本研究中，比较了早产儿和足月儿乳牙釉质和牙本质的化学成分，并研究了化学成分与形态外观之间的关系。使用X射线微分析（XRMA）对14名孕周低于29周的儿童的17颗脱落乳牙的釉质和牙本质进行了研究，并与36颗足月儿脱落乳牙进行了比较。与对照组牙齿相比，早产儿牙齿在整个釉质外层的碳（C）相对值较高、钙（Ca）相对值较低、钙/磷（Ca/P）比值较低以及Ca/C比值较低。在牙本质中，在牙本质-牙髓交界处，磷（P）的相对值较高，Ca/P比值较低。Ca/P比值表明釉质和牙本质晶体中的羟基磷灰石正常。釉质主体和外层较低的Ca/C比值表明釉质孔隙较多。
