Dadzie Ophelia E, Neat Michael, Emley Andrew, Bhawan Jag, Mahalingam Meera
St. John's Institute of Dermatology, London, UK.
Am J Dermatopathol. 2011 Feb;33(1):1-13; quiz 14-6. doi: 10.1097/DAD.0b013e3181d7a2c0.
Advances made within the field of genomics and proteomics have facilitated the emergence of a new era of molecular diagnostics. However, ongoing rapid developments in molecular methodology ensure that this remains a complex field, accessible primarily to scientists who routinely utilize these techniques. For this reason, in this article we provide a concise overview of established and emerging molecular methods and discuss their role as diagnostic adjuncts in Dermatopathology. Important nonmolecular techniques that are used in conjunction with molecular methods are also highlighted.
基因组学和蛋白质组学领域取得的进展推动了分子诊断新时代的出现。然而，分子方法的持续快速发展确保了这仍然是一个复杂的领域，主要是经常使用这些技术的科学家才能涉足。因此，在本文中，我们简要概述了已确立和新兴的分子方法，并讨论了它们在皮肤病理学中作为诊断辅助手段的作用。还强调了与分子方法结合使用的重要非分子技术。
