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抗结核治疗大量腹水患者:F-18-氟脱氧葡萄糖正电子发射断层扫描的作用。

Antituberculosis treatment for a patient with massive ascites: the role of f-18-fluorodeoxyglucose positron emission tomography.

机构信息

From the Division of Obstetrics and Gynecology, Niigata University, Graduate School of Medical and Dental Sciences, and PET Imaging Center, Tachikawa Medical Center, Niigata, Japan.

出版信息

Obstet Gynecol. 2010 Aug;116 Suppl 2:523-525. doi: 10.1097/AOG.0b013e3181e7747f.

Abstract

BACKGROUND

The diagnosis of peritoneal tuberculosis (TB) is difficult, and the condition is often misdiagnosed as advanced ovarian cancer. The clinical discrimination is important to avoid both unnecessary surgery and a delay in anti-TB treatment.

CASE

A 66-year-old woman presented with abdominal distension. Positron emission tomography (PET) with F18-fluorodeoxyglucose showed a diffuse F18-fluorodeoxyglucose accumulation on the entire peritoneum. The presumptive diagnosis was peritoneal TB, and anti-TB treatment was thus started. Follow-up F18-fluorodeoxyglucose-PET revealed the disappearance of the pathologic foci and a decreased peak standardized uptake value.

CONCLUSION

F18-fluorodeoxyglucose-PET may be a helpful tool in the diagnosis of peritoneal TB and serial F18-fluorodeoxyglucose-PET plays a potentially important role in monitoring the treatment response. The peak standardized uptake value may also be helpful for making a quantitative assessment of the therapeutic response.

摘要

背景

腹膜结核(TB)的诊断较为困难,常被误诊为晚期卵巢癌。临床鉴别十分重要,可避免不必要的手术和延误抗结核治疗。

病例

一名 66 岁女性因腹胀就诊。氟代脱氧葡萄糖 F18(F18-fluorodeoxyglucose)正电子发射断层扫描(PET)显示整个腹膜弥漫性 F18-fluorodeoxyglucose 蓄积。初步诊断为腹膜结核,因此开始抗结核治疗。随访 F18-fluorodeoxyglucose-PET 显示病灶消失,摄取峰值标准摄取值降低。

结论

氟代脱氧葡萄糖 F18-PET 可能有助于诊断腹膜结核,且连续氟代脱氧葡萄糖 F18-PET 在监测治疗反应方面发挥着重要作用。摄取峰值标准摄取值也有助于对治疗反应进行定量评估。

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