Department of Biomedical Engineering, Oregon Heath & Science University, Portland, Oregon 97239, USA.
Opt Lett. 2010 Jan 1;35(1):91-3. doi: 10.1364/OL.35.000091.
We present a method to image refractive index distribution within a sample across 8 mm dimension with high spatial resolution by a transmission low-coherence interferometer. The relative strong forward-scattering light is collected, from which the parallel projections of refractive indices within the sample are obtained. A convolution backprojection algorithm is used to transform the projection data set recorded at sufficient angular views into the spatial distribution of refractive indices within the sample. We experimentally demonstrate this method by imaging a phantom. We show that this method can achieve a precision of 0.01 in determining the refractive index and a spatial resolution of 40 microm.
我们提出了一种方法,通过传输低相干干涉仪在 8 毫米的尺寸范围内对样品的折射率分布进行成像,具有高空间分辨率。收集相对强的前向散射光,从中获得样品内部折射率的平行投影。使用卷积反投影算法将在足够角度视图下记录的投影数据集转换为样品内部折射率的空间分布。我们通过对一个模型进行实验演示验证了这种方法。我们表明,该方法可以在确定折射率方面达到 0.01 的精度,并且空间分辨率为 40 微米。