National University Hospital, Lower Kent Ridge Road, Singapore.
Clin Exp Ophthalmol. 2010 May;38(4):418-26. doi: 10.1111/j.1442-9071.2010.02254.x.
This paper aims to compare the efficacy, mean operative time and adverse effects of primary external dacryocystorhinostomy (DCR) versus primary endonasal DCR in treating acquired nasolacrimal duct obstruction. Searches were performed for studies comparing the two procedures. Two reviewers independently extracted data from 14 eligible studies. A random effects model was used to analyse the studies. Outcome measures were defined as patency of the nasolacrimal canal and mean operative time,and adverse effects as cutaneous scarring and bleeding.Both procedures were comparable in efficacy in terms of full success, partial success and anatomic patency. Subgroup analysis showed no significant difference between prospective and retrospective studies as well as between non-laser endonasal DCR versus external DCR and laser endonasal DCR versus external DCR. Endonasal DCR had a significantly shorter mean operative duration, be it laser endonasal DCR (mean difference: 37.65 min, 95% confidence intervals:3.54-71.75 min, P: 0.03) or non-laser endonasal DCR (mean difference: 19.22 min, 95% confidence intervals: 2.15-36.28 min, P: 0.03). The odds of post-operative bleeding was not significantly different between the two procedures, whereas post-operative cutaneous scarring was unique to external DCR and occurred in 50 out of 402 (12.44%) external DCRs recorded. Endonasal DCR has comparable success rates with external DCR and has a shorter operative time and no cutaneous scar. However, drawbacks include the steep learning curve and higher costs.
本文旨在比较原发性外鼻内泪囊吻合术(DCR)与原发性经鼻内 DCR 治疗后天性鼻泪管阻塞的疗效、平均手术时间和不良反应。检索了比较两种手术的研究。两位审查员独立从 14 项合格研究中提取数据。使用随机效应模型分析研究。结局指标定义为鼻泪管通畅和平均手术时间,不良反应定义为皮肤瘢痕和出血。两种手术在完全成功、部分成功和解剖通畅方面的疗效相当。亚组分析显示,前瞻性研究与回顾性研究、非激光经鼻内 DCR 与外 DCR 以及激光经鼻内 DCR 与外 DCR 之间无显著差异。经鼻内 DCR 的平均手术时间明显更短,无论是激光经鼻内 DCR(平均差异:37.65 分钟,95%置信区间:3.54-71.75 分钟,P:0.03)还是非激光经鼻内 DCR(平均差异:19.22 分钟,95%置信区间:2.15-36.28 分钟,P:0.03)。两种手术术后出血的可能性无显著差异,而术后皮肤瘢痕仅见于外 DCR,在记录的 402 例外 DCR 中有 50 例(12.44%)发生。经鼻内 DCR 与外 DCR 具有相当的成功率,手术时间更短,无皮肤瘢痕。然而,缺点包括陡峭的学习曲线和更高的成本。