Olmer M, Ducros J, Grandvuillemin M, Salvadori J M
Sem Hop. 1977 May 23;53(20):1147-53.
95 patients with essential uncomplicated hypertension were mostly submitted to measurement of plasma renin activity, plasma volume and exchangeable sodium. According to the results of the plasma renin activity, we noted variations in blood volume and exchangeable sodium in order to determine the best possible treatment based on these data. Single treatment, based either on diuretics or beta-blockaders was rarely sufficient to bring the blood pressure down to normal. Association of these two types of drug was often very useful. Finally, a critical study of these 3 parameters was made in an economic view of investigations of the blood pressure. The plasma volume seemed to us the most useful investigation, after which came the measurement of plasma renin activity. for the exchangeable sodium seemed of little interest.
95例原发性单纯性高血压患者大多接受了血浆肾素活性、血浆容量和可交换钠的测定。根据血浆肾素活性的结果，我们注意到血容量和可交换钠的变化，以便根据这些数据确定最佳治疗方案。单纯使用利尿剂或β受体阻滞剂进行治疗很少能使血压降至正常。这两种药物联合使用通常非常有效。最后，从血压调查的经济学角度对这三个参数进行了批判性研究。在我们看来，血浆容量似乎是最有用的检查，其次是血浆肾素活性的测定。而可交换钠似乎没什么意义。
