Laboratory for Molecular and Functional Imaging,UMR 5231 CNRS/Université Bordeaux 2, Bordeaux, France.
NMR Biomed. 2010 Nov;23(9):1103-8. doi: 10.1002/nbm.1526.
The objective of this study was to evaluate the feasibility of integrating real-time ultrasound echo guidance in MR-guided high-intensity focused ultrasound (HIFU) heating of mobile targets in order to reduce latency between displacement analysis and HIFU treatment. Experiments on a moving phantom were carried out with MRI-guided HIFU during continuous one-dimensional ultrasound echo detection using separate HIFU and ultrasound imaging transducers. Excellent correspondence was found between MR- and ultrasound-detected displacements. Real-time ultrasound echo-based target tracking during MR-guided HIFU heating is shown with the dimensions of the heated area similar to those obtained for a static target. This work demonstrates that the combination of the two modalities opens up perspectives for motion correction in MRI-guided HIFU with negligible latency.
本研究旨在评估在实时超声回波引导下将移动目标的磁共振引导高强度聚焦超声（HIFU）加热集成的可行性，以减少位移分析和 HIFU 治疗之间的延迟。在使用单独的 HIFU 和超声成像换能器进行连续一维超声回波检测的同时，对移动体模进行了 MRI 引导 HIFU 实验。MR 和超声检测到的位移之间存在极好的一致性。实验结果表明，实时超声回波引导下的 HIFU 加热中的目标跟踪与静态目标获得的加热区域尺寸相似。这项工作表明，两种模式的结合为 MRI 引导 HIFU 中的运动校正开辟了前景，且延迟时间可以忽略不计。
