Department of Digestive Diseases, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain.
Rev Esp Enferm Dig. 2010 Jul;102(8):501-4. doi: 10.4321/s1130-01082010000800009.
In the present paper, we report the case of a patient with long-standing Crohn s disease and multiple complications that, after receiving treatment with infliximab, was diagnosed with an adenocarcinoma of the rectum and anus that required radical surgery, later presenting multiple metastases. In the discussion, characteristics and major risk factors for colorectal cancer in patients with inflammatory bowel disease will be largely reviewed, and current studies will be analyzed in connection with the appearance of neoplasms in patients being treated with biologics.
在本论文中，我们报告了一例患有长期克罗恩病和多种并发症的患者。该患者在接受英夫利昔单抗治疗后，被诊断出患有直肠和肛门腺癌，需要进行根治性手术，随后出现了多处转移。在讨论中，我们将大量回顾炎症性肠病患者结直肠癌的特征和主要危险因素，并分析与接受生物制剂治疗的患者出现肿瘤有关的现有研究。
