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人员呼吸区七氟醚浓度与蒸发器填充相结合,符合职业接触限值。

Personnel breathing zone sevoflurane concentration adherence to occupational exposure limits in conjunction with filling of vaporisers.

机构信息

Foot & Ankle Surgical Centre, Stockholm, Sweden.

出版信息

Acta Anaesthesiol Scand. 2010 Oct;54(9):1117-20. doi: 10.1111/j.1399-6576.2010.02280.x. Epub 2010 Jul 28.

DOI:10.1111/j.1399-6576.2010.02280.x
PMID:20670313
Abstract

BACKGROUND

Work place pollution during filling of anaesthetic vaporisers has been a matter of concern. We studied personnel breathing zone ambient air sevoflurane concentrations during filling of sevoflurane with three different filling systems: Quik-Fil™ for Abbott and Dräger Fill™ resp. Easy-Fil™ adapters for Baxter sevoflurane bottles, referred to as 'Abbott and Baxter filling systems'.

METHOD

Sequential filling of three vaporisers was performed for a 15-min period, once with each of Abbott and Baxter filling systems, by four nurses. Ambient-air sevoflurane p.p.m. concentration in the breathing zone was continuously measured using a Miran 1a device during filling, and the mean 15 min sevoflurane concentration was calculated.

RESULTS

All eight measured (4 × 2 sequences) 15-min mean breathing zone sevoflurane concentrations covering filling of three vaporisers were well below the recommended short-term value (STV) provided by the Swedish Work Environment Authority (STV 20 p.p.m.).

CONCLUSION

The breathing zone sevoflurane concentration during filling of sevoflurane with Baxter or Abbott filling systems, in an ordinary operating theatre, was found to be reassuringly below the Swedish recommended STV (20 p.p.m. average for a 15-min period).

摘要

背景

在麻醉蒸发器填充过程中工作场所污染一直是人们关注的问题。我们研究了在使用三种不同填充系统(雅培的 Quik-Fil™ 和德尔格的 Dräger Fill™ 适配器分别用于 Baxter 七氟醚瓶,即“雅培和 Baxter 填充系统”)填充七氟醚期间,操作人员呼吸区环境空气中七氟醚浓度。

方法

四名护士依次用雅培和 Baxter 填充系统各填充三个蒸发器 15 分钟。在填充过程中,使用 Miran 1a 设备连续测量呼吸区环境空气中的七氟醚 ppm 浓度,并计算 15 分钟的平均七氟醚浓度。

结果

所有 8 次测量(4×2 序列)涵盖三个蒸发器填充的 15 分钟平均呼吸区七氟醚浓度均远低于瑞典工作环境管理局(瑞典工作环境管理局)规定的短期推荐值(STV)(20ppm)。

结论

在普通手术室中使用 Baxter 或 Abbott 填充系统填充七氟醚时,呼吸区七氟醚浓度被发现令人放心地低于瑞典推荐的 STV(15 分钟内平均 20ppm)。

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Acta Anaesthesiol Scand. 2010 Oct;54(9):1117-20. doi: 10.1111/j.1399-6576.2010.02280.x. Epub 2010 Jul 28.
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引用本文的文献

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Validation of Waste Anaesthetic Gas Exposure Limits When Using a Closed Vaporizer Filling System: A Laboratory-Based Study.验证使用封闭蒸发器填充系统时的废气麻醉气体暴露极限:一项基于实验室的研究。
Adv Ther. 2020 Jan;37(1):450-456. doi: 10.1007/s12325-019-01159-2. Epub 2019 Dec 4.
2
Multi-capillary column-ion mobility spectrometry (MCC-IMS) as a new method for the quantification of occupational exposure to sevoflurane in anaesthesia workplaces: an observational feasibility study.多毛细管柱-离子淌度谱(MCC-IMS)作为一种新方法,用于定量评估麻醉工作场所中职业接触七氟醚的情况:一项观察性可行性研究。
J Occup Med Toxicol. 2015 Mar 27;10:12. doi: 10.1186/s12995-015-0056-7. eCollection 2015.