Suzuki S
First Department of Internal Medicine, Yokohama City University School of Medicine, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Mar;29(3):285-92.
Chest wall movement and respiratory muscle strength in patients with neuromuscular diseases was studied. Amyotrophic lateral sclerosis, myasthenia gravis and polymyositis were included. Anterior-posterior (AP) and lateral (LT) diameters of the chest wall were measured at the levels of the 2nd and 5th rib, and the abdomen, using 6 pairs of pneumo-magnetometer. Paradoxical movement of LT was often observed in most diseases. Furthermore, both AP and LT of the abdomen showed a paradoxical movement. This paradoxical movement was augmented in resistive loaded breathing and maximum voluntary ventilation. Baseline pulmonary function was minimally disturbed, except for an increase in RV. However, maximum respiratory muscle strength of both inspiratory and expiratory muscles was decreased to approximately 40% of the predicted. This study suggests that neuromuscular diseases may involve the respiratory muscle in the relatively early stage of the disease.
对神经肌肉疾病患者的胸壁运动和呼吸肌力量进行了研究。纳入了肌萎缩侧索硬化症、重症肌无力和多发性肌炎患者。使用6对肺磁强计在第2和第5肋骨水平以及腹部测量胸壁的前后径（AP）和左右径（LT）。在大多数疾病中经常观察到左右径的矛盾运动。此外，腹部的前后径和左右径均出现矛盾运动。这种矛盾运动在阻力负荷呼吸和最大自主通气时增强。除残气量增加外，基线肺功能受到的干扰最小。然而，吸气肌和呼气肌的最大呼吸肌力量均降至预测值的约40%。这项研究表明，神经肌肉疾病可能在疾病相对早期就累及呼吸肌。
