Blokhina N P, Ketiladze E S, Kelli E I, Viazov S O
Klin Med (Mosk). 1991 Mar;69(3):85-8.
Variants of chronic hepatitis delta (CHD) course were studied in 94 patients. Slow progress (for decades) occurred most frequently, while rapid progress to hepatic cirrhosis (for 1-2 years) or benign course presenting as greater than 3-year remission were rare findings. In addition to routine therapeutic modalities, except corticosteroids, 43 CHD patients received recombinant alpha 2-interferon (reaferon). Follow-up results evaluated separately for hepatic cirrhosis and free of it CHD patients support clinical promise of Soviet recombinant alpha 2-interferon against CHD.
对94例慢性丁型肝炎（CHD）患者的病程变异情况进行了研究。病程进展缓慢（长达数十年）最为常见，而快速进展为肝硬化（1 - 2年）或呈超过3年缓解期的良性病程则较为罕见。除常规治疗方式外，除皮质类固醇外，43例CHD患者接受了重组α2干扰素（reaferon）治疗。对肝硬化患者和未患肝硬化的CHD患者分别进行评估的随访结果支持苏联产重组α2干扰素治疗CHD的临床前景。
