Makarova M G, Sergiev V P, Supriaga V G, Polevoĭ N I
Med Parazitol (Mosk). 1991 Jan-Feb(1):58-9.
The Soviet anthelminthic agent medamine has been synthesized at the Institute of Medical Parasitology and Tropical Medicine, USSR Ministry of Public Health and the Institute of Plant Chemistry, Academy of Sciences of the Uzbek SSR and is produced at the Tashkent Chemical Pharmaceutical Plant. It is used for one-day treatment of enterobiasis which is to be repeated in 2-3 weeks. A daily drug dose is 10 mg per kg body weight, given 3 times a day after meals. The efficacy of therapy was 92 +/- 4% and 100 +/- 2% after the first and second course of treatment, respectively.
苏联驱虫药美达明已由苏联卫生部医学寄生虫学和热带医学研究所与乌兹别克苏维埃社会主义共和国科学院植物化学研究所合成，并在塔什干化学制药厂生产。它用于治疗蛲虫病，疗程为一天，2至3周后需重复治疗。每日药物剂量为每公斤体重10毫克，一日三次，饭后服用。第一疗程和第二疗程治疗后的疗效分别为92±4%和100±2%。
