Levi A D, Wallace M C, Bernstein M, Walters B C
Division of Neurosurgery, Toronto Hospital, Ontario, Canada.
Neurosurgery. 1991 Jun;28(6):859-63. doi: 10.1097/00006123-199106000-00012.
We retrospectively reviewed the incidence rate of clinical postoperative deep vein thrombosis and/or pulmonary embolism in 1703 patients undergoing initial craniotomy for meningioma, glioma, or cerebral metastasis. The incidence rate of clinical thromboembolic complications was 1.59% for all tumor groups within the first 4 weeks of surgery. Patients undergoing surgery for meningiomas had a statistically significant increased risk of thromboembolism despite fewer overall perioperative risk factors, when compared with the other tumor groups. The tumor-specific incidence rates of deep vein thrombosis and/or pulmonary embolism for meningioma, glioma, and metastasis were 3.09%, 0.97%, and 1.03%, respectively. Whether this difference was a result of increased surgical time or an inherent property of meningiomas could not be ascertained.
我们回顾性分析了1703例因脑膜瘤、胶质瘤或脑转移瘤首次接受开颅手术患者术后临床深静脉血栓形成和/或肺栓塞的发生率。在术后4周内，所有肿瘤组临床血栓栓塞并发症的发生率为1.59%。与其他肿瘤组相比，脑膜瘤手术患者尽管围手术期总体危险因素较少，但血栓栓塞风险在统计学上显著增加。脑膜瘤、胶质瘤和转移瘤的深静脉血栓形成和/或肺栓塞的肿瘤特异性发生率分别为3.09%、0.97%和1.03%。无法确定这种差异是手术时间延长的结果还是脑膜瘤的固有特性。
