Chen Amy Y-Y, Zirwas Matthew J, Heffernan Michael P
Wright State University Boonshoft School of Medicine, Department of Dermatology, Dayton, OH 45408, USA.
J Drugs Dermatol. 2010 Jul;9(7):829-34.
Nephrogenic systemic fibrosis (NSF) is a recently described, debilitating systemic disease most commonly seen in patients with renal insufficiency. Exposure to gadolinium-containing contrast agent has been associated with the onset of symptoms. The epidemiology, pathogenesis, clinical manifestation, diagnosis, histolopathology, differential diagnosis and treatment will be reviewed. Clinicians should have a high index of suspicion in susceptible individuals.
肾源性系统性纤维化(NSF)是一种最近被描述的、使人衰弱的全身性疾病,最常见于肾功能不全患者。接触含钆造影剂与症状的发作有关。本文将对其流行病学、发病机制、临床表现、诊断、组织病理学、鉴别诊断及治疗进行综述。临床医生应对易感个体保持高度的怀疑指数。