Institute of Pharmaceutical Sciences, Department of Pharmacognosy, Karl-Franzens-University Graz, 8010 Graz, Austria.
J Nat Prod. 2010 Aug 27;73(8):1381-4. doi: 10.1021/np100263e.
In the course of a study on lignan profiles of tropical and subtropical members of the Magnoliaceae, Magnolia garrettii, an evergreen tree known from northern Thailand, Vietnam, and southern Yunnan (China), was investigated. The work resulted in the isolation of two dimeric lignans from the dichloromethane extract of the leaves of M. garrettii, garrettilignan A (1) and garrettilignan B (2), each substituted with two additional p-allylphenolic moieties. Garrettilignans A (1) and B (2) represent new skeletal types within the neolignan class. Additionally, four known neolignans, magnolol, honokiol, 4'-methylhonokiol, and obovatol, were identified.
在对木兰科热带和亚热带成员的木脂素谱进行研究的过程中，研究了来自泰国北部、越南和中国云南南部的常绿乔木——Garrettia garrettii。这项工作从 M. garrettii 的叶子的二氯甲烷提取物中分离出两种二聚木脂素，分别是garrettilignan A（1）和 garrettilignan B（2），它们每个都有两个额外的 p-丙烯基酚部分取代。Garrettilignans A（1）和 B（2）代表新的神经醇类骨架类型。此外，还鉴定出了四种已知的神经醇类化合物，分别是厚朴酚、厚朴酚、4'-甲基厚朴酚和橄榄醇。
